Outcomes following active surveillance of men with localized prostate cancer diagnosed in the prostate specific antigen era

The Journal of Urology
Barbara ErcolePeter Albertsen

Abstract

We gained insights concerning outcomes associated with men who elect active surveillance for the management of localized prostate cancer. This is a retrospective case series analysis of 40 patients diagnosed with localized prostate cancer since 1990 who elected active surveillance. A total of 31 patients remained on active surveillance for a median of 48 months (range 12 to 168). The 5-year probability of remaining on active surveillance was 74%. Most patients who abandoned this strategy did so within 33 months of diagnosis (range 12 to 84). An increasing prostate specific antigen and anxiety were the 2 most common reasons. A delay in treatment did not appear to compromise subsequent outcomes. Men with low grade prostate cancer can elect active surveillance and have excellent long-term results.

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Citations

Nov 24, 2011·Prostate Cancer·Kristene Myklak, Shandra Wilson
Jan 1, 2009·Cancer Management and Research·Shandra Wilson
Jun 25, 2014·Der Urologe. Ausg. A·K LelligC Stief
Mar 17, 2009·European Urology·Patrick J BastianFritz Schröder
Mar 13, 2014·Journal of Surgical Oncology·Frederik B ThomsenPeter Iversen
Dec 29, 2012·Journal of the National Cancer Institute. Monographs·Jonathan Bergman, Mark S Litwin
Jan 16, 2010·Revista do Colégio Brasileiro de Cirurgiões·Aissar Eduardo NassifHelio Jorge Pozzobon
May 27, 2011·Acta Oncologica·Rodolfo MontironiDaniel M Berney

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