Outcomes following implementation of symptom triggered diagnostic testing for ovarian cancer

European Journal of Obstetrics, Gynecology, and Reproductive Biology
Nirmala RaiSudha Sundar

Abstract

UK is the first country to implement symptom triggered testing for suspected ovarian cancer (OC) following guidance from National Institute of Clinical Excellence in 2011. We evaluated its impact on cancer outcomes and implications on clinical practice. This is a cohort study and we analysed data for all new urgent referrals for suspected OC from two large teaching hospitals using a prospectively collected electronic referral database, supplemented with clinical data from electronic records. We evaluated outcomes prior to (2011) and after (2013) implementation of guidance to evaluate stage shift, referrals workload and surgical procedures generated. Secondary care received 2185 new referrals from primary care for women with suspected gynaecological cancer in post guideline cohort. Of these, 217 women were referred for suspected OC. 90% of primary care referrals were not compliant with guidance. Following implementation of guidance, more women with OC were diagnosed through urgent referral (rapid access clinics): Almost double, 21 of the total 67 (31.34%) OCs in 2013 (post guidance) in comparison to only 11 of 69 OCs (15.94%) were diagnosed in 2011 (pre guidance) through urgent referrals, p=0.03. The predictive value of detectin...Continue Reading

References

Jun 17, 2005·BJOG : an International Journal of Obstetrics and Gynaecology·Clare R BankheadJoan Austoker
Aug 27, 2009·BMJ : British Medical Journal·William HamiltonDeborah Sharp
Oct 8, 2009·BMJ : British Medical Journal·Graham Wheatley
Feb 9, 2011·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Marian K PittsJudy M Simpson
Feb 26, 2011·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayDonald Maxwell Parkin
Apr 23, 2011·BMJ : British Medical Journal·C RedmanUNKNOWN Guideline Development Group
Sep 24, 2011·Nature Reviews. Cancer·Sebastian VaughanFrances R Balkwill
Jul 4, 2012·Gynecologic Oncology·Camille MaringeUNKNOWN ICBP Module 1 Working Group
Feb 21, 2013·BMC Women's Health·Esther L MossHelen Stokes-Lampard
Jan 28, 2014·Obstetrics and Gynecology·M Robyn AndersenBarbara A Goff

❮ Previous
Next ❯

Citations

Oct 29, 2015·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Matthew BarclayAndrew Nordin
Oct 18, 2018·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Mark J A RietveldNicole P M Ezendam
Mar 9, 2019·Molecular and Clinical Oncology·Julie L HentzeEstrid V Høgdall
Jun 8, 2021·Scandinavian Journal of Primary Health Care·Marie-Louise Ladegaard BaunPeter Vedsted

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Cancer Incidence & Mortality

Cancer has emerged as a global concern due to its increase in incidence and mortality. Efforts are underway to evaluate and develop action plans to reduce the global burden of cancer. Currently, lung cancer, breast cancer and prostate cancer are the leading causes of cancer mortality. Here is the latest research on cancer incidence and mortality.

Related Papers

The British Journal of General Practice : the Journal of the Royal College of General Practitioners
Chris Smith
© 2021 Meta ULC. All rights reserved