Abstract
The influence of drug misuse on outcomes following primary total hip (THA) or knee (TKA) arthroplasty is poorly understood. The National Hospital Discharge Survey was used to identify patients who underwent primary THA or TKA between 1990 and 2007. Patients were divided into two groups: 1) those with a diagnosis of drug misuse (cannabis, opioids, cocaine, amphetamines, sedatives, inhalants or mixed combinations) (n=13,163) and 2) those with no diagnosis of misuse (n=8,366,327). Patients with a diagnosis of drug misuse had longer hospital stays (P<0.001), nearly eight times the odds of leaving against medical advice (P<0.001) and five times the mortality rate (P<0.001). Drug misuse was associated with higher odds (P<0.001) of complications including postoperative infection, anemia, convulsions, osteomyelitis, and blood transfusion.
References
Nov 24, 1993·JAMA : the Journal of the American Medical Association·S LemeshowJ Rapoport
Sep 15, 1998·Psychiatric Services : a Journal of the American Psychiatric Association·K P PagesD S Cowley
Oct 14, 1998·Health Affairs·D McKusickJ S Genuardi
Jul 8, 1999·The New England Journal of Medicine·D P PhillipsN M Ryan
Apr 5, 2001·The American Journal of Medicine·S D Halpern, C C Mechem
Apr 18, 2001·The Journal of Arthroplasty·C R LehmanA B Davidson
May 5, 2001·BMJ : British Medical Journal·UNKNOWN UK Collaborative Group on Monitoring the Transmission of HIV Drug Resistance
Feb 13, 2002·Kennedy Institute of Ethics Journal·UNKNOWN National Reference Center for Bioethics Literature
Oct 18, 2002·The Lancet Infectious Diseases·Franklin D Lowy, Maureen Miller
Nov 4, 2005·The New England Journal of Medicine·Rachel J Gordon, Franklin D Lowy
Aug 18, 2006·British Journal of Anaesthesia·G E HillE R Johnson
May 9, 2007·Archives of General Psychiatry·Wilson M ComptonBridget F Grant
Oct 14, 2008·The Journal of Trauma·Gabriel E Ryb, Carnell Cooper
Feb 11, 2009·The Journal of Trauma·Pantelis HadjizachariaDemetrios Demetriades
Jun 15, 2011·The Journal of Infection·Parham SendiWerner Zimmerli
Nov 8, 2011·Administration and Policy in Mental Health·Rima TawkRoss Mullner
Feb 14, 2012·The Journal of Arthroplasty·Yi-Hsun YuMel S Lee
Apr 6, 2012·Archives of Orthopaedic and Trauma Surgery·Karl WieserClaudio Dora
Sep 4, 2012·BMJ Open·Gabriel AgboadoLynn Donkin
Dec 1, 2012·Psychosomatics·Ottokar StundnerStavros G Memtsoudis
Mar 13, 2014·Clinical Orthopaedics and Related Research·Daniel D BohlJonathan N Grauer
Mar 19, 2014·Journal of Shoulder and Elbow Surgery·Arjan G J BotDavid Ring
May 30, 2014·Surgical Infections·Rajesh RamanathanTherese M Duane
Aug 16, 2014·Materia Socio-medica·Shirzad Asadollah Pour KarimiMohammad Asadi Abokheily
Citations
Nov 4, 2015·The Knee·Abiram BalaMichael P Bolognesi
May 18, 2016·The Journal of Arthroplasty·Brian T NickelMichael P Bolognesi
Mar 2, 2016·The Journal of Sexual Medicine·Alejandra BalenRicardo Munarriz
Sep 23, 2016·The Journal of Bone and Joint Surgery. American Volume·James T NinomiyaStephen J Incavo
Mar 13, 2018·Clinical Orthopaedics and Related Research·Siddharth A MahureRan Schwarzkopf
Jan 23, 2018·Journal of Orthopaedic Trauma·Spencer SummersVictor Hugo Hernandez
Feb 17, 2018·Orthopedics·Mitchell R KlementThorsten M Seyler
Jan 10, 2018·World Journal of Orthopedics·Samuel RosasVictor H Hernandez
Oct 20, 2018·Journal of Orthopaedic Trauma·Luis GrauOmri Merose
Nov 15, 2017·The Kaohsiung Journal of Medical Sciences·Yu-Jie SuChung-Hwan Chen
Nov 22, 2019·Substance Use & Misuse·Edmund GradyElango Edhayan
Apr 7, 2020·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Stephanie A ChenRoniel Weinberg
Mar 10, 2020·Spine·Janis BekerisStavros G Memtsoudis
Oct 2, 2020·Orthopedics·Sahitya K DenduluriNicholas J Giori
Jul 25, 2017·JB & JS Open Access·Siddharth A MahureRan Schwarzkopf
May 15, 2018·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Brian T NickelThorsten M Seyler
May 10, 2020·Current Reviews in Musculoskeletal Medicine·Casey M O'ConnorAndrew J Rosenbaum
Apr 6, 2018·Geriatric Orthopaedic Surgery & Rehabilitation·Luis GrauVictor Hugo Hernandez
Sep 4, 2018·Clinics in Orthopedic Surgery·Keith T AzizHarpal S Khanuja
Jun 9, 2020·Archives of Orthopaedic and Trauma Surgery·Georgios OrfanosBishoy Youssef
Jan 25, 2020·The Journal of Arthroplasty·Rushabh M VakhariaMartin W Roche
Nov 20, 2020·Regional Anesthesia and Pain Medicine·Jenna McAfeeErin E Bonar
Mar 3, 2020·Injury·Shea M ComadollPaul E Matuszewski
Apr 23, 2021·Journal of Addictive Diseases·Jasvinder Singh
Oct 13, 2020·Journal of the American Medical Directors Association·Kevin T PritchardKenneth J Ottenbacher
Jun 29, 2021·JAMA Network Open·Ahmed K EmaraNicolas S Piuzzi
Sep 19, 2020·The Journal of the American Academy of Orthopaedic Surgeons·Venkatsaiakhil TirumalaYoung-Min Kwon
Jul 2, 2021·The Bone & Joint Journal·Rushabh M VakhariaMichael A Mont