Outcomes following transsphenoidal surgical management of incidental pituitary adenomas: a series of 52 patients over a 17-year period

Journal of Neurosurgery
Justin SeltzerGabriel Zada

Abstract

OBJECTIVEIncidental pituitary adenomas (IPAs) are commonly discovered during cranial imaging evaluations obtained for unrelated indications. The optimal management of IPA remains controversial. The authors investigated the outcomes and safety of the surgical treatment of IPAs at their institution.METHODSClinical outcome data for 1692 patients surgically treated for pituitary adenomas at the Keck Medical Center of USC/USC Pituitary Center over a 17-year period (1999-2016) were reviewed to identify all cases with surgically managed IPAs. Clinical characteristics reviewed in this retrospective analysis included patient demographics, endocrine laboratory data, visual field examinations, and MRI results. Intraoperative data reviewed included requirement for CSF leak repair, surgical complications, and estimated extent of resection. Postoperative data collected included pathology results, length of stay, postoperative complications, endocrine outcomes, readmission rates, and long-term outcomes, including extent of resection noted on postoperative imaging studies and tumor progression and/or recurrence.RESULTSFifty-two patients (3.1% of all cases) underwent transsphenoidal surgery for IPA. The median age at surgery was 61 years (range...Continue Reading

References

Jul 1, 1995·Surgical Neurology·B K Kleinschmidt-DeMastersJ C Stears
Oct 1, 1996·The Journal of Clinical Endocrinology and Metabolism·P U FredaK D Post
Jan 16, 1998·Endocrinology and Metabolism Clinics of North America·M E Molitch
Jul 31, 2003·European Journal of Endocrinology·Naoko SannoYuzuru Kato
Jul 27, 2004·Cancer·Shereen EzzatIan E McCutcheon
Dec 17, 2008·Cleveland Clinic Journal of Medicine·Dina SerhalAmir H Hamrahian
Dec 1, 2009·Best Practice & Research. Clinical Endocrinology & Metabolism·Mark E Molitch
Jul 16, 2010·Pituitary·Benjamin R RandallWilliam T Couldwell
Apr 8, 2011·The Journal of Clinical Endocrinology and Metabolism·Pouyan FaminiShlomo Melmed
Apr 9, 2011·The Journal of Clinical Endocrinology and Metabolism·Pamela U FredaUNKNOWN Endocrine Society
Feb 7, 2012·Best Practice & Research. Clinical Endocrinology & Metabolism·I BancosV M Montori
Feb 7, 2012·Best Practice & Research. Clinical Endocrinology & Metabolism·Israel B OrijaAmir H Hamrahian
Nov 23, 2013·Clinical Neurology and Neurosurgery·Mahmoud MessererEmmanuel Jouanneau
Jun 10, 2015·Annales d'endocrinologie·Françoise GallandPhilippe Chanson
Oct 2, 2015·European Journal of Endocrinology·Tomas Thor AgustssonRafn Benediktsson
Apr 16, 2017·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Zhichao GaoZhipeng Su

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Software Mentioned

Research Electronic Data Capture ( REDCap )
REDCap

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.