Outcomes From Selective Use of Thrombectomy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction: An Analysis of the British Cardiovascular Intervention Society/National Institute for Cardiovascular Outcomes Research (BCIS-NICOR) Registry, 2006-2013

JACC. Cardiovascular Interventions
Alex SirkerBritish Cardiovascular Intervention Society (BCIS)

Abstract

This study used a large national cohort to examine patterns of thrombectomy use in ST-segment elevation myocardial infarction (STEMI) and the relationship to mortality. The impact of coronary thrombectomy on mortality in STEMI has not been definitively established. Published trial data have been insufficiently powered to address this. The U.K. national registry was used to study 98,176 patients treated with primary percutaneous coronary intervention (PCI), between January 1, 2006, and December 31, 2013. Patients were grouped on the basis of whether they received thrombectomy or not; subgroups of simple (manual aspiration) and complex (mechanical) thrombectomy were also evaluated. The primary endpoint was 30-day mortality. The principal adjusted analysis used propensity score matching (PSM). A sensitivity analysis was performed using logistic regression controlled for the propensity score. Thrombectomy use markedly increased in the United Kingdom between 2008 and 2010 but plateaued thereafter at slightly below 50% of all primary PCI cases. No significant mortality difference was seen, in adjusted analyses, between the overall thrombectomy group and the no thrombectomy group, at 30 days or 1 year (at 30 days, PSM average treatmen...Continue Reading

References

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Citations

Feb 14, 2017·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·André LuzHenrique Carvalho
Oct 19, 2017·Circulation. Cardiovascular Interventions·Junhua GePeter Nordbeck
Oct 4, 2016·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Eddie D Brown, James C Blankenship
Jan 5, 2019·Journal of the American Heart Association·Murat SezerSabahattin Umman
Aug 14, 2018·Medical & Biological Engineering & Computing·Hongtao WangPeng Chen
Apr 16, 2020·Current Problems in Cardiology·Syed Mustajab HasanJigar Patel
Nov 7, 2020·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·C A BargonH A Rakhorst

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