Outcomes in Trials for Management of Caries Lesions (OuTMaC): protocol

Trials
Falk SchwendickeNicola Innes

Abstract

Clinical trials on caries lesion management use an abundance of outcomes, hampering comparison or combination of different study results and their efficient translation into clinical practice. Core outcome sets are an agreed standardized collection of outcomes which should be measured and reported in all trials for a specific clinical area. We aim to develop a core outcome set for trials investigating management of caries lesions in primary or permanent teeth conducted in primary or secondary care encompassing all stages of disease. To identify existing outcomes, trials on prevention and trials on management of caries lesions will be screened systematically in four databases. Screening, extraction and deduplication will be performed by two researchers until consensus is reached. The definition of the core outcome set will by based on an e-Delhi consensus process involving key stakeholders namely patients, dentists, clinical researchers, health economists, statisticians, policy-makers and industry representatives. For the first stage of the Delphi process, a patient panel and a separate panel consisting of researchers, clinicians, teachers, industry affiliated researchers, policy-makers, and other interested parties will be held...Continue Reading

Associated Clinical Trials

Citations

Mar 12, 2016·Journal of Dentistry·Deborah GrunerFalk Schwendicke
Apr 14, 2016·Journal of Dentistry·Padhraig S FlemingNikolaos Pandis
Jun 14, 2019·International Journal of Dentistry·Abdulmonem A AlshihriMohammed S Aldossary
Jan 21, 2021·International Journal of Paediatric Dentistry·Helen Jessica RogersChristopher Robert Vernazza
Jul 23, 2021·PloS One·Thomas J LamontKatie Gillies
Aug 2, 2021·Trials·Danchen QinUNKNOWN Core Outcome Set for trials on the prevention and treatment of enamel White Spot Lesions (COS-WSL) group
Aug 10, 2021·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Yunlei WangUNKNOWN Core Outcome Set for trials on the prevention and treatment of enamel White Spot Lesions (COS-WSL) group

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