Outcomes of 27-Gauge Vitrectomy-Assisted Choroidal and Subretinal Biopsy

Ophthalmic Surgery, Lasers & Imaging Retina
Dilraj S GrewalPrithvi Mruthyunjaya

Abstract

To report the initial experience of 27-gauge vitrectomy-assisted choroidal and subretinal biopsy PATIENTS AND METHODS: Retrospective, interventional case series. Eighteen eyes of 18 patients undergoing 27-gauge vitrectomy-assisted choroidal (n = 16) or subretinal biopsy (n = 2). Clinical and lesion characteristics, cytopathology, histology, gene expression profiling (GEP), visual acuity (VA), complications including vitreous hemorrhage (VH), development of rhegmatogenous retinal detachment (RD), and need for additional surgeries were analyzed. Indications were choroidal melanoma (n = 10), indeterminate choroidal (n = 5), and subretinal lesions (n = 3). Mean lesion height was 3.33 mm ± 1.55 mm (range: 0.80 mm to 6.75 mm) and largest diameter was 8.63 mm ± 4.14 mm (range: 3 mm to 15.5 mm). Mean number of intralesional biopsy passes required was 1.76 ± 0.83 (range: one to four). During a mean follow-up of 7.4 months ± 2.7 months (range: 4 months to 14 months), VA was unchanged (0.5 logMAR ± 0.6 logMAR vs. 0.7 logMAR ± 0.84 logMAR; P = .07). Pathologic diagnosis was obtained in 16 of 18 eyes (88.9%), and GEP data were collected for all 11 choroidal melanomas. Post-biopsy VH occurred in 13 of 18 eyes (72.2%) and was severe enough to...Continue Reading

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Citations

Dec 7, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Michael I SeiderUNKNOWN Ocular Oncology Study Consortium
Jul 10, 2020·JAMA Ophthalmology·Christopher D ConradyThomas J Wubben
May 27, 2020·Journal of Ophthalmology·Zhaoxin JiangXiaoyan Ding
Aug 23, 2020·Indian Journal of Ophthalmology·Reema BansalAtul Kumar
Aug 2, 2019·Cancers·Luisa FrizzieroRaffaele Parrozzani
Oct 24, 2020·International Ophthalmology Clinics·Basil K Williams, Maura Di Nicola
Nov 7, 2019·Case Reports in Ophthalmology·Andrew W KamAdrian T Fung

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