Outcomes of ab interno trabeculectomy with the trabectome after failed trabeculectomy

The British Journal of Ophthalmology
Igor I BusselTrabectome Study Group

Abstract

To evaluate outcomes of ab interno trabeculectomy (AIT) with the trabectome following failed trabeculectomy. Prospective study of AITs and phaco-AITs after a failed trabeculectomy. The indication for AIT was intraocular pressure (IOP) above target on maximally tolerated therapy, and for phaco-AIT a visually significant cataract and need to lower IOP or glaucoma medications. Outcomes included IOP, medications, complications, secondary procedures and success, defined as IOP of less than 21 mm Hg and a greater than 20% reduction from baseline without further surgery. Exclusion criteria were trabeculectomy less than 3 months prior to AIT or follow-up under 1 year. Seventy-three eyes of 73 patients with 1 year follow-up were identified. At 1 year, mean IOP in AIT significantly decreased by 28% from 23.7±5.5 mm Hg, and medications from 2.8±1.2 to 2±1.3 (n=58). In phaco-AIT, the mean IOP decreased 19% from 20±5.9 mm Hg and medications from 2.5±1.5 to 1.6±1.4 (n=15). Transient hypotony occurred in 7%, and further surgery was necessary in 18%. For AIT and phaco-AIT, the 1-year cumulative probability of success was 81% and 87%, respectively. Both AIT and phaco-AIT showed a reduction in IOP and medication use after 1 year, suggesting that...Continue Reading

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Citations

Jan 7, 2016·The British Journal of Ophthalmology·Kevin KaplowitzNils A Loewen
May 11, 2016·Survey of Ophthalmology·Julia K Polat, Nils A Loewen
Sep 7, 2016·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·R A Widder, T S Dietlein
Jun 28, 2016·Clinical & Experimental Ophthalmology·Yalong DangNils A Loewen
May 2, 2016·Experimental Eye Research·Yalong DangNils A Loewen
Mar 30, 2018·European Journal of Ophthalmology·Anja-Maria DavidsMatthias K Klamann
Jul 7, 2018·Journal of Glaucoma·Lauriane SalinasKaweh Mansouri
Nov 6, 2018·Journal of Glaucoma·Masayuki KasaharaKazuhiro Matsumura
Apr 30, 2019·Journal of Cataract and Refractive Surgery·Hamed EsfandiariNils A Loewen
Jun 15, 2017·Medicine·Constance O OkekeTrabectome Study Group
Apr 13, 2020·International Ophthalmology·Mehmet Ozgur CubukErkan Unsal
Sep 17, 2020·Annual Review of Vision Science·David J Mathew, Yvonne M Buys
Sep 23, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Y Al YousefNils A Loewen
May 18, 2017·Journal of Ophthalmology·David Z Chen, Chelvin C A Sng
May 31, 2018·Investigative Ophthalmology & Visual Science·Susannah WaxmanNils A Loewen
May 23, 2017·F1000Research·Katherine FallanoNils A Loewen
Sep 28, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Hamed EsfandiariNils A Loewen
Jan 1, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Milena PahlitzschEckart Bertelmann
May 7, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Si ChenNils A Loewen
Sep 26, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Tigran KostanyanNils A Loewen
Dec 3, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·A StrzalkowskaNils A Loewen

Related Concepts

Teens
Glaucoma
Physiologic Intraocular Pressure
Repeat Surgery
Intraocular Pressure Test
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Trabeculotomy
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