Outcomes of cardiac transplantation in septuagenarians

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Daniel J GoldsteinDavid D'Alessandro

Abstract

Cardiac transplantation in many centers is programmatically limited to patients aged younger than 70 years. We investigated the trends and outcomes for cardiac transplantation in recipients aged 70 years and older in the United States. De-identified data were provided by United Network of Organ Sharing. Transplant recipients were grouped by age 60-69 years and 70 years and older. Univariate comparisons were performed using Student's t-test or the Pearson chi-square test. Survival was estimated using the Kaplan-Meier technique and compared with the log-rank test. Cox regression was used to determine predictors of death after transplant. Statistical significance was assigned to p < 0.05. Between January 1, 1998, and June 15, 2010, 5,807 sexagenarians and 332 septuagenarians received allografts. The septuagenarian cohort had more men, less diabetes, was less likely to have a ventricular assist device, and more likely to be status II. Donors for septuagenarians were older and died more frequently from intracranial hemorrhage. Median unadjusted survival was 9.8 years for sexagenarians vs 8.5 years for septuagenarians (p = 0.003). There was no difference in the incidence of cerebrovascular accident, length of stay, or pacemaker need ...Continue Reading

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Citations

Jun 24, 2014·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Eugene C DePasqualeHeather J Ross
May 12, 2012·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Sharon Ann Hunt
Jan 19, 2016·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Mandeep R MehraUNKNOWN International Society for Heart Lung Transplantation (ISHLT) Heart Failure and Transplantation Council
Dec 4, 2015·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Lauren B CooperChetan B Patel
Dec 17, 2014·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Eulàlia RoigUNKNOWN rest of the participants of the Spanish Heart Transplantation Registry
Feb 28, 2017·Current Opinion in Cardiology·Nikhil Bassi, Valluvan Jeevanandam

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