Outcomes of dual adult kidney transplants in the United States: an analysis of the OPTN/UNOS database

Transplantation
Jagbir GillSuphamai Bunnapradist

Abstract

The organ shortage has resulted in increased use of kidneys from expanded criteria donors (ECD). For ECD kidneys unsuitable for single use, dual kidney transplants (DKT) may be possible. There are limited data comparing outcomes of DKT to single kidney ECD transplants, making it unclear where DKT fits in the current allocation scheme. Our purpose was to compare outcomes of DKT and ECD transplants in the United States. From 2000 to 2005, a total of 625 DKT, 7686 single kidney ECD, and 6,044 SCD transplants from donors aged>or=50 years were identified from the Organ Procurement and Transplantation Network/United Network for Organ Sharing data. Allograft survival was the primary outcome. DKT comprised 4% of kidney transplants from donors aged>or=50 years. Compared to the ECD donor group, the DKT donor group was older (mean age 64.6+/-7.7 years vs. 59.9+/-6.2 years) and consisted of more African Americans (13.1% vs. 9.9%), and more diabetic donors (16.3% vs. 10.4%; P<0.001). Mean cold ischemic time was longer in DKT (22.2+/-9.7 hr), but rates of delayed graft function were lower (29.3%) compared to ECD transplants (33.6%, P=0.03). Three-year overall graft survival was 79.8% for DKT and 78.3% for ECD transplants. DKT were infrequent...Continue Reading

References

Jul 13, 1999·Journal of the American College of Surgeons·C M LeeE J Alfrey
Feb 11, 2003·The Journal of Urology·Richard S LeeChristian S Kuhr
Mar 28, 2003·Journal of the American Society of Nephrology : JASN·Suphamai BunnapradistYong W Cho
Apr 16, 2003·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Robert A MetzgerRobert M Merion
Apr 30, 2003·Transplantation·Edward J AlfreyUNKNOWN Dual Kidney Registry
Apr 28, 2004·Clinical Transplantation·Mario SénéchalIradj Gandjbakhch
Apr 26, 2005·Transplantation Proceedings·U BoggiF Mosca
Jun 10, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Jesse D ScholdHerwig-Ulf Meier-Kriesche
Jan 27, 2006·The New England Journal of Medicine·Giuseppe RemuzziUNKNOWN Dual Kidney Transplant Group
May 12, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·L MatsuokaR Selby
Jun 15, 2006·Transplant International : Official Journal of the European Society for Organ Transplantation·Burcin EkserPaolo Rigotti

❮ Previous
Next ❯

Citations

Jan 30, 2010·Nature Reviews. Nephrology·Burcin Ekser, Paolo Rigotti
Jun 23, 2009·Transplantation·Andrea ColliniMario Carmellini
May 7, 2011·Transplantation·Anja GallinatGeorgios C Sotiropoulos
Dec 17, 2008·Journal of the American Society of Nephrology : JASN·Markus GiessingLutz Liefeldt
Feb 26, 2013·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Kamran KhanmoradiJorge A Ortiz
Oct 17, 2013·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Peter BalazEva Pokorna
Sep 18, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·UNKNOWN European Renal Best Practice Transplantation Guideline Development Group
Jul 1, 2014·Current Opinion in Organ Transplantation·Umberto Maggiore, Paolo Cravedi
Jul 18, 2009·Current Opinion in Organ Transplantation·Neeraj SinghTodd Pesavento
Mar 16, 2013·Current Opinion in Organ Transplantation·Helmut Hopfer, Éva Kemény
Jan 13, 2016·Transplant International : Official Journal of the European Society for Organ Transplantation·Anne-Hélène QuerardFlorence Gillaizeau
Feb 9, 2012·Transplantation Proceedings·Y H KimD J Han
Apr 20, 2010·Urology·Pierfrancesco VerouxMassimiliano Veroux
Feb 12, 2009·Clinical Transplantation·Moro O SalifuDale A Distant
Oct 22, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·R SnanoudjM Delahousse
Aug 8, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·T KlairL K Kayler
Jul 20, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·B EkserP Rigotti
Feb 4, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·P L TsoM L Henry
Jun 19, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·L Fernández-LorenteJ M Cruzado
Jan 30, 2014·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·B TanrioverM A Hardy
Aug 12, 2014·Clinical Transplantation·E Lledó-GarcíaJ Pascual
Aug 16, 2013·International Journal of Urology : Official Journal of the Japanese Urological Association·William HanfRicardo Codas
Aug 27, 2014·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·I GandolfiniU Maggiore
May 15, 2015·Transplantation Reviews·Mariana Wohlfahrtova, Ondrej Viklicky
Dec 30, 2014·BMC Nephrology·Carlo GrifasiAndrea Renda
Jun 4, 2015·Transplantation Proceedings·Y AawsajD Talbot
Jun 23, 2011·Transplantation Proceedings·B NardoA Faenza
Apr 30, 2013·Transplantation Proceedings·S V ImpedovoP Ditonno
Mar 5, 2016·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·D E StewartM I Aeder
Oct 11, 2016·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·R ThuretM O Timsit
Nov 3, 2016·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Suphamai Bunnapradist, Gabriel M Danovitch
Oct 18, 2016·Transplantation·Renaud SnanoudjChristophe Legendre
Jan 11, 2017·Transplantation·María José Pérez-SáezJulio Pascual
May 20, 2017·Clinical Transplantation·Kim Chi TranPatrick P Luke
Dec 30, 2017·Clinical Transplantation·Giuseppe OrlandoRobert J Stratta
Mar 28, 2018·Transplant International : Official Journal of the European Society for Organ Transplantation·Nuria MonteroJulio Pascual
Aug 10, 2017·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Piero RuggenentiPaolo Rigotti
May 18, 2018·Transplant International : Official Journal of the European Society for Organ Transplantation·Lionel MendelDaniel Chevallier
May 10, 2018·Clinical Transplantation·Muhammad A KhanRobert J Stratta
Mar 2, 2018·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Grigoriy ShekhtmanSuphamai Bunnapradist
Apr 28, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·B Hippen
Oct 5, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·P T SattianayagamJ D Gillmore

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
R SnanoudjM Delahousse
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Burcin EkserPaolo Rigotti
The New England Journal of Medicine
Maria Rosaria RaspolliniGian Luigi Taddei
© 2021 Meta ULC. All rights reserved