Outcomes of endoscopic resection for superficial duodenal epithelial neoplasia

Gastrointestinal Endoscopy
Naohisa YahagiToshio Uraoka

Abstract

Pancreaticoduodenectomy is an invasive procedure, and endoscopic resection (ER) is an alternative therapy. However, details regarding the outcomes of ER are unknown, especially for superficial duodenal epithelial neoplasia (SDET). The aim of this study was to elucidate the outcomes of ER for SDET and to compare EMR with endoscopic submucosal dissection (ESD). This was a retrospective observational study. From June 2010 to June 2017, 320 cases of endoscopically resected SDET (146 EMR-treated cases and 174 ESD-treated cases) were included in this study. We analyzed the proportions of en bloc resection, R0 resection, perforation, and bleeding as outcomes of ER and compared outcomes between the EMR and ESD groups. Next, we collected data on the features and clinical course of cases with adverse events. The proportions of en bloc resection and R0 resection among all cases were 96.6% and 83.4%, respectively. In over 95% of cases, ESD achieved en bloc resection, regardless of lesion size. The incidences of perforation and bleeding were 8.8% and 3.4%, respectively, and the former was largely successfully managed by conservative treatment. The mortality rate was 0%, and all patients were discharged with a median hospital stay of 8.5 day...Continue Reading

Citations

Sep 24, 2019·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Atsushi NakayamaNaohisa Yahagi
Jul 17, 2019·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Yasushi YamasakiHiroyasu Iishi
Sep 10, 2019·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Yoshiyuki KiguchiNaohisa Yahagi
May 18, 2020·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Yorimasa YamamotoHaruhiro Inoue
Jan 31, 2020·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Yosuke ToyaTakayuki Matsumoto
Sep 9, 2020·Endoscopy International Open·Motohiko Kato, Naohisa Yahagi
Feb 21, 2019·World Journal of Gastroenterology : WJG·Yuko HaraHisao Tajiri
Sep 4, 2020·World Journal of Gastrointestinal Oncology·Mitsuru EsakiYoshihiro Ogawa
Jan 1, 2021·Scandinavian Journal of Gastroenterology·Kingo HirasawaShin Maeda
Dec 2, 2020·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Seiichiro FukuharaNaohisa Yahagi
Jan 9, 2021·Scandinavian Journal of Gastroenterology·Naomi KakushimaHiroyuki Ono
Jan 5, 2021·World Journal of Clinical Cases·Xiao-Yu LiKun-Peng Zhang
Jul 14, 2020·Endoscopy·Mariano VillarroelIgnacio Zubiaurre
Aug 28, 2020·Gastrointestinal Endoscopy·Motohiko KatoNaohisa Yahagi
Mar 5, 2021·Clinical Journal of Gastroenterology·Shunya TakayanagiKen Ohata
Mar 12, 2021·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Osamu GotoKatsuhiko Iwakiri
Apr 27, 2021·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Hyo-Joon Yang
Jul 5, 2021·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Yasushi YamasakiUNKNOWN D-UEMR Study Group
Jul 29, 2021·Journal of Gastroenterology and Hepatology·Yosuke ToyaTakayuki Matsumoto
Aug 10, 2021·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Yusaku TakatoriNaohisa Yahagi

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