Outcomes of Impella 5.0 in Cardiogenic Shock: A Systematic Review and Meta-analysis

Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery
George BatsidesMark B Anderson

Abstract

The aim of the study was to comprehensively summarize the survival outcomes and complications of Impella 5.0 (Abiomed Inc, Danvers, MA USA) use in patients with cardiogenic shock (CS). We performed a literature review for relevant studies by searching in Medline, Medline In-Process, EMBASE, and the CENTRAL bibliographic databases on April 30, 2017. Nonoverlapping studies with 10 patients or more supported for cardiogenic shock with Impella 5.0 or Impella left direct were included. Data on patient characteristics, indication of support, and outcomes were extracted. A random effect was used to pool the various outcomes. This meta-analysis included six studies totaling 163 patients (mean ± SD age = 56.3 ± 12.0, male 81%). Indications for support included 88 (54.0%) for acute on chronic decompensated heart failure, 35 (21.5%) for postcardiotomy cardiogenic shock, 27 (16.6%) for acute myocardial infarction complicated by cardiogenic shock, and, 13 (8.0%) for cardiogenic shock due to other reasons. Survival to next therapy was 73.5% in patients supported for acute on chronic decompensated heart failure. The survival to device explant among patients supported for postcardiotomy cardiogenic shock or acute myocardial infarction complica...Continue Reading

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Citations

Jul 5, 2019·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Charles-Henri DavidGuillaume Lebreton
Feb 9, 2019·BMC Cardiovascular Disorders·Uma ChandrasekaranHaroon Faraz
Jun 17, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Danny RamzyMark Anderson
Jul 8, 2020·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Kenji NishimuraTomoki Shimokawa
Jun 21, 2020·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Hideo OishiToyoaki Murohara
Nov 9, 2020·ESC Heart Failure·Andrea MontisciFederico Pappalardo
Jan 6, 2021·General Thoracic and Cardiovascular Surgery·Yu InabaYasunari Sakamoto
Jan 28, 2021·ClinicoEconomics and Outcomes Research : CEOR·Alexandre Le GuyaderGuillaume Lebreton
Mar 19, 2021·Frontiers in Pediatrics·Muhammad Bakr GhbeisRavi Ram Thiagarajan
Dec 22, 2020·The Annals of Thoracic Surgery·Mark AndersonJason Williams
May 7, 2021·Current Heart Failure Reports·Alexandra E SperryMichael Ibrahim
May 26, 2021·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Alexander M BernhardtSebastian Schulte-Eistrup
Jul 13, 2021·The International Journal of Artificial Organs·Carly FabrizioEdward T Horn
Mar 21, 2021·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Adhitya RamamurthiLucian A Durham
Jan 25, 2022·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Hiroaki HiraiwaToyoaki Murohara

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