Outcomes of in-hospital cardiopulmonary resuscitation for patients with end-stage liver disease

Liver International : Official Journal of the International Association for the Study of the Liver
Nneka N UfereBarret Rush

Abstract

There have been improving survival trends after in-hospital cardiac arrest for the general population, but there is limited information on the outcomes of hospitalized patients with end-stage liver disease (ESLD) who undergo cardiopulmonary resuscitation (CPR). We aimed to examine survival to hospital discharge after receipt of in-hospital CPR in patients with ESLD using a nationally representative sample. We used the Nationwide Inpatient Sample database from 2006 to 2014 to identify adult patients who underwent in-hospital CPR. Using multivariate modelling, we compared survival to hospital discharge for patients with ESLD to those without ESLD. We also compared outcomes of patients with ESLD to patients with metastatic cancer. A total of 177 533 patients underwent in-hospital CPR, of which 1474 (0.8%) had ESLD. Patients with ESLD had lower rates of survival to hospital discharge compared to patients without ESLD (10.7% vs 28.6%, P < 0.01). In multivariate modelling, ESLD was significantly associated with lower odds of survival to hospital discharge after in-hospital CPR (OR 0.35, 95% CI 0.28-0.44, P < 0.01). Among survivors of in-hospital CPR, ESLD patients had a significantly lower chance of discharge to home compared to pati...Continue Reading

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Citations

Aug 14, 2020·Journal of the American Heart Association·Richard T CarrickDavid M Kent
May 18, 2020·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Ruben HernaezHugo R Rosen
Oct 2, 2020·Journal of the American College of Emergency Physicians Open·Oscar J L MitchellBenjamin S Abella
Jul 9, 2021·Journal of Community Hospital Internal Medicine Perspectives·William R Swindell, Christopher G Gibson
Nov 1, 2021·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Nneka N UfereAreej El-Jawahri

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