Outcomes of infants receiving chronic peritoneal dialysis: an analysis of the USRDS registry

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
Keia R SandersonBradley A Warady

Abstract

Outcome data for infants on chronic peritoneal dialysis (CPD) is limited and has been based primarily on the analyses of voluntary entry registry data. In contrast, the United States Renal Data Systems (USRDS) collects data on all infants with end-stage kidney disease (ESKD) on chronic dialysis in the USA. We aimed to describe the clinical characteristics of this population and to determine the associated patient mortality. The USRDS database was reviewed retrospectively for data on infants who initiated CPD at ≤ 12 months of age from 1990 to 2014. Infants were categorized into four groups, CPD initiation age (≤ 1 month of age or neonates and > 1-12 months of age or older infants) and initiation era (1990-1999 and 2000-2014). A total of 1723 infants (574 neonates and 1149 older infants) were identified. Overall, 20.9% of infants (147 neonates and 213 older infants) died on dialysis during the follow-up. The most commonly identified causes of death on dialysis were cardiorespiratory disease (25.8%) and infection (22.8%). There was an increased risk for mortality in all infants who initiated CPD in the earlier initiation era (1990-1999) vs the later era (2000-2014) (aHR of 1.95), for females vs males (aHR 1.43), and for those wit...Continue Reading

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Citations

Nov 23, 2018·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Keia R Sanderson, Bradley A Warady
Nov 2, 2019·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Eugene Y H ChanUNKNOWN International Pediatric Peritoneal Dialysis Network
Aug 23, 2019·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Aaron Wightman
Jun 7, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Ryoko HaradaKenji Ishikura

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