Outcomes of Left Ventricular Assist Device Implantation in Patients With Uncommon Etiology Cardiomyopathy

The American Journal of Cardiology
Vincent GalandRaphaël P Martins

Abstract

The impact of uncommon etiology cardiomyopathies on Left-ventricular assist device (LVAD)-recipient outcomes is not very well known. This study aimed to characterize patients with uncommon cardiomyopathy etiologies and examine the outcomes between uncommon and ischemic/idiopathic dilated cardiomyopathy. This observational study was conducted in 19 centers between 2006 and 2016. Baseline characteristics and outcomes of patients with uncommon etiology were compared to patients with idiopathic dilated/ischemic cardiomyopathies. Among 652 LVAD-recipients included, a total of 590 (90.5%) patients were classified as ischemic/idiopathic and 62 (9.5%) patients were classified in the "uncommon etiologies" group. Main uncommon etiologies were: hypertrophic (n = 12(19%)); cancer therapeutics-related cardiac dysfunction (CTRCD) (n = 12(19%)); myocarditis (n = 11(18%)); valvulopathy (n = 9(15%)) and others (n = 18(29%)). Patients with uncommon etiologies were significantly younger with more female and presented less co-morbidities. Additionally, patients with uncommon cardiomyopathies were less implanted as destination therapy compared with ischemic/idiopathic group (29% vs 38.8%). During a follow-up period of 9.1 months, both groups experi...Continue Reading

References

Apr 13, 2000·The New England Journal of Medicine·G M FelkerE K Kasper
Sep 1, 2007·The New England Journal of Medicine·Leslie W MillerUNKNOWN HeartMate II Clinical Investigators
Jul 18, 2009·Journal of the American College of Cardiology·Francis D PaganiUNKNOWN HeartMate II Investigators
Nov 19, 2009·The New England Journal of Medicine·Mark S SlaughterUNKNOWN HeartMate II Investigators
Feb 27, 2013·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Athanasios TsiourisJeffrey A Morgan
Jun 25, 2016·Journal of the American College of Cardiology·Alan G JappSanjay K Prasad
Jul 17, 2016·Journal of Cardiothoracic Surgery·A KornbergerA Beiras Fernandez
Oct 4, 2017·Journal of Cardiac Failure·Snehal R PatelDaniel J Goldstein
Sep 22, 2018·JACC. Clinical Electrophysiology·Vincent GalandUNKNOWN ASSIST-ICD Investigators

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