Outcomes of patients implanted with a left ventricular assist device at nontransplant mechanical circulatory support centers

The American Journal of Cardiology
Marc R KatzArash Salemi

Abstract

The goal of this study was to assess outcomes of patients who underwent implantation of left ventricular assist devices (LVADs) at nontransplantation mechanical circulatory support centers. As the availability of LVADs for advanced heart failure has expanded to nontransplantation mechanical circulatory support centers, concerns have been expressed about maintaining good outcomes. Demographics and outcomes were evaluated in 276 patients with advanced heart failure who underwent implantation of LVADs as bridge to transplantation or destination therapy at 27 open-heart centers. Baseline characteristics, operative mortality, length of stay, readmission rate, adverse events, quality of life, and survival were analyzed. The overall 30-day mortality was 3% (8 of 276), and survival rates at 6, 12, and 24 months, respectively, were 92±2%, 88±3%, and 84±4% for the bridge-to-transplantation group and 81±3%, 70±5%, and 63±6% for the destination therapy group, comparable with results published by the national Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS). The median length of stay for all patients was 21 days. Bleeding was the most frequent adverse event. Stroke occurred in 4% (bridge to transplantation) and...Continue Reading

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Citations

Feb 6, 2013·The American Journal of Emergency Medicine·You Hwan JoJoong Eui Rhee
Oct 1, 2016·JACC. Heart Failure·Robb D Kociol
Oct 17, 2017·Scandinavian Cardiovascular Journal : SCJ·Erica HolmbergBengt Peterzén
Sep 19, 2018·Clinical Cardiology·Mustafa M AhmedJuan M Aranda
May 12, 2018·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Saurabh GuptaRanjit John
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Oct 21, 2015·Current Cardiology Reports·Julie L Rosenthal, Randall C Starling
Aug 5, 2017·Journal of cardiovascular ultrasound·Matteo CameliSergio Mondillo

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