Outcomes of pregnancies complicated by beta-thalassemia/hemoglobin E disease

International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
Suchaya LuewanTheera Tongsong

Abstract

To assess the outcomes of pregnancies affected by beta-thalassemia/hemoglobin E (beta-thal/HbE) disease. A retrospective cohort study was conducted with 54 women with singleton pregnancies complicated by beta-thal/HbE disease only. The controls-to-cases ratio was 2:1. Although maternal outcomes were similar in both groups, gestational age at birth and birth weight were significantly lower in the study group and the cesarean delivery rate was significantly higher in that group (relative risk [RR], 2.1). The incidences of fetal growth restriction, preterm birth, and low birth weight were also significantly higher in the study group, with RRs of 2.8, 2.7, and 5.6, respectively. Pregnancies affected by beta-thal/HbE disease were significantly associated with an increased risk of fetal growth restriction, preterm birth, and low birth weight.

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Citations

May 18, 2013·Archives of Gynecology and Obstetrics·Tharangrut HanprasertpongSavitree Pranpanus
Apr 30, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Walairat KemthongTheera Tongsong
Feb 15, 2011·Translational Research : the Journal of Laboratory and Clinical Medicine·Abdul V SaadiKapaettu Satyamoorthy
Aug 27, 2010·Brain & Development·Viroj Wiwanitkit
Oct 20, 2015·Archives of Gynecology and Obstetrics·Chitrakan CharoenboonTheera Tongsong
Jun 30, 2015·Journal of Postgraduate Medicine·R MerchantRoshan B Colah
Sep 15, 2016·Hemoglobin·Khushnooma ItaliaRoshan B Colah
Jun 11, 2017·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Kuntharee TraisrisilpTheera Tongsong
Jul 28, 2016·Maternal and Child Health Journal·Supatra SirichotiyakulTheera Tongsong

Related Concepts

Fetal Growth Retardation
Hemoglobin E
Low Birth Weight Infant
Neonatal Prematurity
Pregnancy Complications, Hematologic
Pregnancy Outcome
Retrospective Studies
Incidence Studies
Thalassemia Minor
High-Risk Pregnancy

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