Outcomes of stent insertion and mortality in obstructive stage IV colorectal cancer patients through 10 year duration.

Surgical Endoscopy
Yong Eun ParkTae Il Kim

Abstract

Colorectal stents are frequently used in patients with stage IV colorectal cancer with obstruction. However, there are only few studies on changes in outcomes of these patients and on the effect of stents on outcome over a long period of time with ongoing changes in therapeutic strategy, including chemotherapy. We retrospectively evaluated 353 patients with bowel obstruction in stage IV colorectal cancer who underwent colonic stenting between years 2005 and 2014. The study population was divided into three groups based on time periods: 2005-2008, 2009-2011, and 2012-2014. The frequency of colorectal stent insertion procedure increased over the time periods (13.8%, 18.3%, and 20.8%, respectively). There were no changes in success rate and total complication rate. However, the early complication rate in the 3rd period was significantly lower than in the other periods (15.4% vs. 17.1% vs. 7.2%; P = 0.039). In the multivariate analysis, carcinomatosis (hazard ratio, 1.478; 95% confidence interval, 1.016-2.149; P = 0.041) and covered or partial-covered stent (hazard ratio, 1.733; 95% confidence interval, 1.144-2.624; P = 0.009; hazard ratio, 1.988; 95% confidence interval, 1.132-3.493; P = 0.017, respectively) were associated with i...Continue Reading

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Aug 23, 2019·Asian Journal of Endoscopic Surgery·Aik Yong ChokRonnie Mathew
Feb 5, 2021·Journal of the Anus, Rectum and Colon·Akihisa MatsudaHiroshi Yoshida
Jun 18, 2021·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·Benno Arnstadt, Hans-Dieter Allescher

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