Abstract
To evaluate the outcomes of trabeculectomy with mitomycin-C (MMC) in uveitis associated with Vogt-Koyanagi-Harada disease (VKH). Retrospective cohort study included 27 eyes of 15 patients with uveitic glaucoma associated with VKH disease who underwent trabeculectomy with MMC as a first glaucoma procedure at King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia between 1992 and 2011. The main outcome measures were: the intraocular pressure (IOP), the number of antiglaucoma medications, the presence of visually threatening complications, and the need for further surgeries to control the IOP. The mean follow-up was 78.19 months. The IOP decreased significantly from a mean of 40.15±7.0 to 13.12±6.9 mm Hg on the last follow-up (P<0.01) as well as during the whole follow-up period. The number of medications needed to control the IOP also decreased significantly from 3.89±0.6 to 1.04±1.3. The cumulative probabilities of success were 77.8%, 74.1%, 63.0%, and 51.9% at 12, 24, 36, and 48 months postoperatively, respectively. The most common complications were cataract development and progression (53.8%), hypotony (IOP≤5 mm Hg) (33.3%), choroidal effusion (7.4%), and decompressive retinopathy (7.4%). Eight eyes (29.6%) needed a second...Continue Reading
References
May 1, 1977·American Journal of Ophthalmology·S OhnoG R O'Connor
Jan 1, 1995·Survey of Ophthalmology·R S MoorthyN A Rao
May 1, 1993·Ophthalmology·D J ForsterG Baerveldt
May 5, 2001·American Journal of Ophthalmology·R W ReadM Usui
Jul 26, 2002·Journal of Glaucoma·Elizenda M CeballosMichael J Lynn
Nov 10, 2004·Journal of Glaucoma·Ilgaz Sagdic YalvacSunay Duman
May 14, 2005·Current Opinion in Neurology·Shwu-Jiuan Sheu
Nov 12, 2005·Current Eye Research·Peizeng YangAize Kijlstra
Feb 14, 2007·Japanese Journal of Ophthalmology·Hiroshi GotoShigeaki Ohno
Apr 17, 2007·International Ophthalmology·Abdullah S Al-KharashiAhmed M Abu El-Asrar
Jul 5, 2008·Current Eye Research·Wang Fang, Peizeng Yang
Apr 18, 2009·Eye·B DupasP LeHoang
Jun 13, 2009·Eye·T KaburakiM Araie
Jul 15, 2009·American Journal of Ophthalmology·Simon K LawJoseph Caprioli
Aug 26, 2010·Ocular Immunology and Inflammation·Hani S Al-MezaineAhmed M Abu El-Asrar
Apr 13, 2011·Journal of Ophthalmic Inflammation and Infection·Ester CarreñoMargarita Calonge
Aug 17, 2012·Journal of Glaucoma·Keiichiro IwaoHidenobu Tanihara
Sep 14, 2012·Acta Ophthalmologica·Ahmed M Abu El-AsrarAbdulrahman M Al-Muammar
Citations
Nov 26, 2008·Survey of Ophthalmology·Efstratios MendrinosTarek Shaarawy
Oct 17, 2017·International Ophthalmology·Faisal A AlmobarakIbrahim Aljadaan
May 17, 2019·Journal of Glaucoma·Vidya WadkeShantha Balekudaru
Dec 4, 2019·International Ophthalmology·Ufuk ElginNilufer Berker
Apr 29, 2019·Survey of Ophthalmology·Qianqian WangDaniel Lee
Jun 8, 2021·International Ophthalmology·Faisal A AlmobarakHassan Aldhibi