Outcomes with respect to disabilities of the upper limb after hand allograft transplantation: a systematic review

Transplant International : Official Journal of the European Society for Organ Transplantation
Luis LandinCesar Casado-Perez

Abstract

The aim of this work is to compare disabilities of the upper limb before and after hand allograft transplantation (HAT), and to describe the side effects of immunosuppressive (IS) agents given to recipients of hand allografts. Clinical cases of HAT published between 1999 and 2011 in English, French, or German were reviewed systematically, with emphasis on comparing disabilities of the arm, shoulder and hand (DASH) scores before and after transplantation. Duration of ischemia, extent of amputation, and time since amputation were evaluated for their effect on intrinsic musculature function. Infectious, metabolic, and oncological complications because of IS therapy were recorded. Twenty-eight patients were reported in 56 clinical manuscripts. Among these patients, disabilities of the upper limb dropped by a mean of 27.6 (±19.04) points on the DASH score after HAT (P = 0.005). Lower DASH scores (P = 0.036) were recorded after secondary surgery on hand allografts. The presence of intrinsic muscle function was observed in 57% of the recipients. Duration of ischemia, extent of transplantation, and time since amputation were not associated statistically with the return of intrinsic musculature function. Three grafts were lost to follow...Continue Reading

References

Jan 1, 1989·The Journal of Hand Surgery·J B JupiterC J Bour
Dec 1, 1994·The Journal of Bone and Joint Surgery. American Volume·A D SaiesR D Fitch
Jun 8, 1999·Plastic and Reconstructive Surgery·V B Doolabh, S E Mackinnon
Jan 26, 2002·The Journal of Hand Surgery·William P CooneyUNKNOWN American Society for Surgery of the Hand
May 25, 2002·Health Affairs·Donald M Berwick
Jul 2, 2003·Annals of Surgery·Jean Michel DubernardEarl Owen
Sep 16, 2003·Transplantation·Jean KanitakisJean-Michel Dubernard
Apr 28, 2004·Transplantation Proceedings·M LanzettaH Kapila
May 29, 2004·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Bertram L KasiskeJon J Snyder
Jul 23, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Stefan SchneebergerRaimund Margreiter
Mar 24, 2005·Annals of Plastic Surgery·John N JensenSusan E Mackinnon
Aug 27, 2005·Transplantation·Stefan SchneebergerHugo Bonatti
Mar 11, 2006·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·F SchuindD Abramowicz
Mar 17, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S SchneebergerR Margreiter
Jul 11, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·P PetruzzoJ M Dubernard
May 22, 2007·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S SchneebergerR Margreiter
Oct 2, 2007·Annales de chirurgie plastique et esthétique·A GazarianA Eljaafari
Nov 15, 2007·Surgical Infections·Hugo BonattiStefan Schneeberger
Dec 20, 2007·Plastic and Reconstructive Surgery·Zvi Margaliot, Kevin C Chung
Jan 25, 2008·The New England Journal of Medicine·Tatsuo KawaiDavid H Sachs
Feb 12, 2008·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S SchneebergerF Schuind
Sep 3, 2008·The Journal of Hand Surgery·Paul Manske
Sep 3, 2008·The Journal of Hand Surgery·Warren C BreidenbachVijay S Gorantla
Oct 14, 2008·Surgery·Kadiyala V RavindraWarren C Breidenbach
Dec 2, 2008·Transplant International : Official Journal of the European Society for Organ Transplantation·Kenneth A Bodziak, Donald E Hricik
Mar 31, 2009·Transplantation Proceedings·G BrandacherS Schneeberger
Mar 31, 2009·Transplantation Proceedings·H BonattiS Schneeberger
Apr 16, 2009·Proceedings of the National Academy of Sciences of the United States of America·Claudia D VargasAngela Sirigu
Apr 28, 2009·The Journal of Hand Surgery, European Volume·P C CavadasJ Ibañez
Jul 22, 2009·Transplant International : Official Journal of the European Society for Organ Transplantation·Irmeli Lautenschlager
Aug 21, 2009·Annals of Plastic Surgery·Chad R Gordon, Maria Siemionow
Sep 11, 2009·Transplantation·Luis LandinFrancisco Vera-Sempere
Jan 6, 2010·Plastic and Reconstructive Surgery·Luis LandinIgnacio Roger
Mar 2, 2010·The Journal of the American Academy of Orthopaedic Surgeons·Jaimie T ShoresW P Andrew Lee
Oct 26, 2010·Transplantation Proceedings·J JableckiD Patrzalek
Nov 6, 2010·Transplantation·Palmina PetruzzoChristian Dumontier
Jan 29, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·L LantieriP Grimbert
Feb 2, 2011·The Journal of Hand Surgery, European Volume·H O KamburoğluA Keçik
Mar 31, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·P PetruzzoE Morelon
Apr 22, 2011·Annals of Plastic Surgery·Pedro C CavadasAlessandro Thione

❮ Previous
Next ❯

Citations

Jul 23, 2013·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Blake D MurphyGregory H Borschel
Jul 6, 2014·Mayo Clinic Proceedings·Harvey ChimSteven L Moran
Sep 18, 2014·The Journal of Hand Surgery·Heather BaltzerSteven J McCabe
Jan 9, 2014·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·Brian T CarlsenJennifer Peterson
Aug 6, 2013·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·Michaela CoenenJoy MacDermid
Mar 16, 2013·Transplant International : Official Journal of the European Society for Organ Transplantation·Theresa HautzStefan Schneeberger
Mar 5, 2013·Clinical Transplantation·Theresa HautzStefan Schneeberger
Apr 16, 2013·Clinical Transplantation·J Rodrigo Diaz-SisoStefan G Tullius
Sep 4, 2012·The Journal of Hand Surgery·Sally E JensenGregory A Dumanian
Aug 25, 2015·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Laurence BernardonLionel Badet
Oct 19, 2013·La Presse médicale·Alain Charles Masquelet
Oct 21, 2015·International Wound Journal·Zhen-Yu ZhangZheng-Gang Bi
Dec 31, 2016·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·K ShanmugarajahC L Cetrulo
Apr 1, 2017·Journal of Materials Science. Materials in Medicine·Jaimie T ShoresGerald Brandacher
Jul 30, 2014·Annals of Plastic Surgery·Gaby DoumitJames E Zins
Nov 20, 2014·The Journal of Hand Surgery, European Volume·U BrüggerU von Wartburg
Apr 24, 2018·Current Opinion in Organ Transplantation·Alyssa WardJedediah K Lewis
Jan 19, 2018·Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of India·Subramania IyerV G Prasad
Jan 19, 2018·Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of India·Mohit SharmaAkshay Omkumar
May 31, 2012·Annals of Plastic Surgery·Jorge BonastreCesar Casado-Perez
Jul 15, 2015·Transplantation·Martin IglesiasJuan Guzman-Gonzalez
Nov 6, 2018·Transplant International : Official Journal of the European Society for Organ Transplantation·Marie ThuongBeatriz Dominguez-Gil
Jan 11, 2019·Annals of Plastic Surgery·C Anton FriesMichael R Davis
Oct 16, 2013·Annals of Plastic Surgery·Pedro Bolado, Luis Landin
Feb 22, 2017·Transplantation·Nicole L WernerKagan Ozer
May 29, 2019·Plastic and Reconstructive Surgery·Carrie A KubiakPaul S Cederna
Jul 22, 2015·Techniques in Hand & Upper Extremity Surgery·Tessa DrijkoningenCurtis L Cetrulo
Mar 8, 2019·Cellular & Molecular Immunology·Jasper IskeStefan G Tullius
Oct 16, 2013·Current Opinion in Organ Transplantation·Maria SiemionowAntonio Rampazzo
Jan 14, 2020·Transplant International : Official Journal of the European Society for Organ Transplantation·Shoubao WangBinbin Sun
Mar 14, 2020·Transplantation·Valentin HaugBohdan Pomahac
Jan 1, 2014·Current Transplantation Reports·Axel Rahmel
Aug 28, 2015·Plastic and Reconstructive Surgery·Antonio RampazzoBahar Bassiri Gharb
Jun 17, 2020·SAGE Open Medicine·John HeinemanSimon G Talbot
Aug 12, 2018·Journal of Surgical Oncology·Branislav KollarBohdan Pomahac
Jan 30, 2021·Microsurgery·Anthony DeLeonibusBahar Bassiri Gharb
Mar 17, 2021·The Journal of Hand Surgery·Sarah E KinsleySimon G Talbot

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Related Papers

Transplant International : Official Journal of the European Society for Organ Transplantation
Theresa HautzStefan Schneeberger
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Palmina PetruzzoJ M Dubernard
© 2022 Meta ULC. All rights reserved