Outdoor air pollutants derived from industrial processes may be causally related to the development of asthma in children

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Y K KimY Y Kim

Abstract

There is no consistent evidence that outdoor air pollutants are involved in the development of asthma. The aim of this study was to determine whether outdoor air pollutants derived from industrial processes were related to the prevalence of asthma, bronchial hyperresponsiveness, and atopy in exposed children. A total of 7,511 children from 7 to 12 years of age were recruited in the study. Eight hundred eighty-eight of 1,009 (88%) of the subjects living around industrial factories and 5,998 of 6,502 (92%) living in a less polluted neighboring area responded to the ISAAC questionnaire. A total of 1,492 subjects 8 to 9 years old underwent skin prick tests for 11 common aeroallergens. A total of 732 of the subjects from 8 to 9 years of age underwent bronchial provocation tests with hypertonic saline (BPT-HS). The prevalence of ever experiencing wheezing and wheeze during the last 12 months was 25.6%, and 18.8% among the children living in the more polluted area. This was significantly higher than for those living in the less polluted area (14.2% and 9.0%, respectively). The positive rate of BPT-HS (the provocative dose of hypertonic saline causing 20% fall of FEV, < or = 23 mL) was higher among those in the more polluted area than ...Continue Reading

References

Oct 1, 1992·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S L JohnstonS T Holgate
Apr 1, 1986·The Journal of Allergy and Clinical Immunology·M MuranakaH Tokiwa
Apr 1, 1987·The Journal of Allergy and Clinical Immunology·S TakafujiM Muranaka
Apr 1, 1986·The Journal of Allergy and Clinical Immunology·A B Murray, B J Morrison
Jun 1, 1995·Archives of Disease in Childhood·L BråbäckB Björkstén
Sep 1, 1994·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·L BråbäckB Björkstén
Feb 1, 1994·American Journal of Respiratory and Critical Care Medicine·E von MutiusH H Thiemann
Feb 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A J Wardlaw
May 1, 1996·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·D H NahmC S Hong
Apr 29, 1998·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·D StrachanH Williams
Oct 16, 1999·The Journal of Allergy and Clinical Immunology·J Q Koenig

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Citations

Jul 9, 2004·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·José Luiz Magalhães RiosAlfeu Tavares França
Oct 25, 2011·The Science of the Total Environment·Marta RavaRoberto de Marco
Jul 2, 2010·Allergy, Asthma & Immunology Research·You-Young Kim

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