PMID: 8593758Jul 1, 1995Paper

Oval pupil in patients with diabetes mellitus: examination by measurement of the dark-adapted pupillary area and pupillary light reflex

Diabetes Research and Clinical Practice
H IsotaniT Utsumi

Abstract

Determination of the dark-adapted pupillary area (DAPA) by infrared photography revealed that some diabetic patients show corectopia (oval pupil) in addition to the small DAPA as pupillary abnormalities. The prevalence and clinical details of oval pupil were compared between diabetic patients and healthy subjects. Pupillary light reflexes were also analyzed with an infrared videopupillography in some of the diabetic patients. The healthy subjects were examined for the influence of age on the ratio of the pupillary diameter of the major and minor axes. The ratio was 1.04 +/- 0.02 (mean +/- S.D.) in the healthy subjects, and cases in which the ratio was +2 S.D. or higher than the mean ratio were defined as oval pupil. Oval pupil was observed in 21 (24%) of 86 diabetic patients, and was correlated with heart rate variation (P < 0.05) and DAPA (P < 0.01), which represent an autonomic dysfunction. Quantitative analysis of pupillary light reflexes with an infrared videopupillography revealed that the dark-adapted pupillary area before photic stimulation (P < 0.01) and the maximum %-velocity of constriction (P < 0.05) were significantly less in the oval pupil group than in the round pupil group. Cranial magnetic resonance imaging reve...Continue Reading

References

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Jul 1, 1960·Archives of Ophthalmology·P GRIMES, L VON SALLMANN

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Citations

Aug 28, 2002·Diabetes Care·Daniel PittaschHendrik Lehnert
Aug 6, 2013·Current Biology : CB·Kenneth P WrightEvan D Chinoy
Feb 23, 2019·Frontiers in Neurology·Fion D Bremner, Allan J Drapkin

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