Ovarian cancer and gangrene of the digits: case report and review of the literature

Mayo Clinic Proceedings
S F Chow, C H McKenna

Abstract

Digital ischemia has been reported with various types of cancer, especially gastrointestinal. It is more common in elderly women than in any other group, and the most common symptom is a gangrenous finger (or fingers). More than half of the patients have metastatic involvement. Once the primary disease has been treated, when feasible, the digital symptoms usually regress or disappear. The presence of digital ischemia without other rheumatologic stigmata or vascular predisposition in an elderly patient should raise clinical suspicion of a paraneoplastic phenomenon. Herein we describe a 65-year old woman with digital ischemia associated with ovarian cancer. The diagnosis was established by biopsy after extremely high levels of cancer antigen 125 were detected.

Citations

Jun 28, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Wendela G PronkAnneke M Westermann
Mar 28, 2008·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·M J BehneI Moll
Apr 25, 2012·Archives of Gynecology and Obstetrics·Shahin RobatiKetan Gajjar
Sep 2, 2011·Acta Obstetricia Et Gynecologica Scandinavica·Synnöve StaffJohanna Mäenpää
May 16, 2012·British Journal of Hospital Medicine·Jolene WitherspoonMichael Lewis
Dec 24, 2002·Current Opinion in Rheumatology·Eliza Chakravarty, Mark C Genovese
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Nov 1, 2002·Head & Neck·Jim R Wright, Susan Gudelis
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Jan 17, 2021·BMJ Case Reports·Sara AlRasbiAbdullah M Al Alawi
Dec 17, 2020·The Journal of Obstetrics and Gynaecology Research·Emad MatanesAmnon Amit

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