PMID: 2123759Nov 1, 1990Paper

Ovarian electrocautery versus human menopausal gonadotrophins and pure follicle stimulating hormone therapy in the treatment of patients with polycystic ovarian disease

Clinical Endocrinology
A Abdel GadirR W Shaw

Abstract

Eighty-eight clomiphene citrate-resistant infertile patients with oligomenorrhoea or amenorrhoea attributable to polycystic ovarian disease were divided at random into three groups. Twenty-nine patients were treated with ovarian electrocautery, 30 with human menopausal gonadotrophins (hMG) and 29 with pure follicle stimulating hormone (FSH). Successful ovulation was induced in 71.4, 70.6 and 66.7% of the cycles in the groups respectively. Ten patients conceived after electrocautery and pure FSH therapy while 15 conceived after hMG medication (chi-squared = 1.6464, P = 0.439). The six-cycle cumulative pregnancy rate in the three consecutive groups was 52.1, 55.4, and 38.3%. Four further pregnancies were achieved after treating 10 patients in the electrocautery group with clomiphene citrate (100 mg/day for 5 days) for 25 cycles. The rate of pregnancy wastage in the corresponding groups was 21.4, 53.3 and 40% (chi-squared = 3.127, P = 0.2039). Ovarian electrocautery is equally effective as hMG and pure FSH in the treatment of PCO patients resistant to clomiphene citrate therapy.

References

Oct 1, 1987·Fertility and Sterility·M Bohrer, E Kemmann
Mar 1, 1985·American Journal of Obstetrics and Gynecology·N GarceaF De Tomasi
Feb 1, 1980·Clinical Endocrinology·S S Yen
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Citations

Sep 28, 1995·The New England Journal of Medicine·S Franks
Mar 1, 1993·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·J VerhelstC Mahler
May 3, 2016·The Cochrane Database of Systematic Reviews·Chi Eung Danforn LimNini Chen
Jul 3, 2019·The Cochrane Database of Systematic Reviews·Chi Eung Danforn LimHui Chen
May 29, 2002·Current Opinion in Obstetrics & Gynecology·Emre Seli, Antoni J Duleba
Sep 10, 2015·The Cochrane Database of Systematic Reviews·Nienke S WeissMadelon van Wely
Feb 13, 2020·The Cochrane Database of Systematic Reviews·Esmée M BordewijkMadelon van Wely
Nov 1, 1993·British Journal of Obstetrics and Gynaecology·P VandekerckhoveT W Harada
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Oct 10, 2001·Human Fertility : Journal of the British Fertility Society·S Nasseri, W L Ledger
Jan 8, 2005·Journal of Endocrinological Investigation·S PalombaF Zullo
Oct 1, 2005·Archives of Gynecology and Obstetrics·Nikiforos BallianGregory A Kaltsas
Aug 25, 2015·The Cochrane Database of Systematic Reviews·David NugentRichard Lilford
Jan 17, 2019·The Cochrane Database of Systematic Reviews·Nienke S WeissMadelon van Wely
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Jun 15, 2012·The Cochrane Database of Systematic Reviews·Cindy FarquharJane Marjoribanks

Related Concepts

Polychemotherapy
Electrocoagulation
Follicle Stimulating Hormone
HMG Lepori
Ovary
Ovarian Stimulation
Sclerocystic Ovaries
Pregnancy Outcome

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