Ovarian mixed germ cell tumor composed of polyembryoma and immature teratoma

Gynecologic Oncology
M TakemoriK Hasegawa

Abstract

We report the case of a 41-year-old woman with ovarian mixed germ cell tumor which was composed of polyembryoma and immature teratoma and who had high serum levels of alpha-fetoprotein (AFP) and human chorionic gonadotropin (hCG). By immunohistochemical methods, AFP was found in yolk sac cells of the embryoid bodies and immature hepatoid tissues, and hCG was found in giant syncytiotrophoblastic cells. She was treated with surgery followed by cisplatin-based combination chemotherapy. She is well, and her serum levels of AFP and hCG have not been elevated for more than 4 years after the treatment.

Citations

Apr 22, 2017·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Jennifer N Stall, Robert H Young
Jan 10, 2002·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Daniel M JondleJo Ann Benda
Oct 25, 2011·Obstetrical & Gynecological Survey·Christine A ParkinsonThankamma V Ajithkumar
Apr 2, 2005·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Sevgi BakarisNurdan Tunali
Aug 1, 2018·Expert Review of Endocrinology & Metabolism·Agedi N Boto, Pei Hui
Aug 1, 2011·Australasian Journal of Ultrasound in Medicine·Lauren Kite, Talat Uppal
Jan 24, 2004·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Angiolo GadducciAndrea Riccardo Genazzani

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