Ovarian mucinous tumor with mural nodules of anaplastic carcinoma.

Gynecologic Oncology
Y F ChanL Ma

Abstract

A case of mucinous cystic ovarian tumor with mural nodules of anaplastic carcinoma in a 30-year-old woman is described. The carcinomatous components within the nodules showed strong immunopositivity for cytokeratin and carcinoembryonic antigen, and ultrastructurally they displayed epithelial and glandular differentiation. Omental metastasis had already developed in the patient, and she received postoperative adjuvant chemotherapy consisting of cyclophosphamide and cis-platinum. No sign of recurrence was evident 4 months after the operation. The literature is reviewed and the importance of adjuvant chemotherapy in the postoperative management of such patients highlighted. The salient pathologic features differentiating mural nodules of anaplastic carcinoma and true sarcoma from prognostically favorable sarcoma-like nodules are presented.

References

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Citations

Mar 1, 1995·Journal of Surgical Oncology·T HamadaY Sasaguri
Jul 15, 2009·Archives of Gynecology and Obstetrics·Tayfun GungorLeyla Mollamahmutoglu
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Jan 29, 2002·The American Journal of Surgical Pathology·Ingrid M Rodríguez, Jaime Prat
Jan 27, 2021·Taiwanese Journal of Obstetrics & Gynecology·Ling-Hui ChuYu-Tso Liao
Dec 3, 1999·Archives of Pathology & Laboratory Medicine·T MizunoT Murase
Jul 20, 2002·Archives of Pathology & Laboratory Medicine·Jorge S Reis-FilhoFernando C Schmitt

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