PMID: 9450243Feb 5, 1998Paper

Ovarian response and FSH profile in cows following injection of various doses of inhibin antiserum

The Journal of Veterinary Medical Science
S AkagiKazuyoshi Taya

Abstract

Dose effect of inhibin antiserum on ovarian response and hormonal profiles were investigated. On day 12 of the estrous cycle (day 0 = estrus), 14 of 19 cows were given a single i.v. injection of 25 ml (n = 4), 37.5 ml (n = 5) or 50 ml (n = 5) antiserum against inhibin produced in a castrated male goat. The other 5 animals were given 50 ml castrated male goat serum (control serum). The animals in each group received a single i.m. injection of 0.5 mg prostaglandin F2 alpha analogue (PG) 48 hr following the serum injection. The population of follicles and ovulation rate (estimated by the number of corpora lutea) were examined by ultrasonography. Administration of inhibin antiserum consistently resulted in a significant (p < 0.01) increase in plasma concentrations of follicle-stimulating hormone (FSH) in inhibin-neutralized groups, although the increased FSH levels were sustained longer in 50-ml group than in the 25- and 37.5- ml groups. Levels in the circulating inhibin antibody titer were positively correlated with dosage of inhibin antiserum. A large number of antral follicles (> or = 4 mm in diameter) developed similarly after hypersecretion of FSH in all neutralized groups, coupled with a rise in plasma estradiol levels, while...Continue Reading

References

Apr 1, 1976·Journal of Animal Science·S E EchternkampH W Hawk
Jan 1, 1992·Journal of Reproduction and Fertility·G P AdamsO J Ginther
Feb 1, 1991·Molecular and Cellular Endocrinology·S G HillierA J Mason
Apr 1, 1974·The Journal of Clinical Endocrinology and Metabolism·S G KorenmanB M Sherman
Aug 1, 1994·Journal of Reproduction and Fertility·S J SunderlandJ J Ireland
Jan 1, 1993·Journal of Reproduction and Fertility·A R ScanlonJ F Roche

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Citations

Sep 30, 2004·Reproduction : the Official Journal of the Society for the Study of Fertility·M S MedanK Taya
Jan 14, 2005·The Journal of Reproduction and Development·Mohamed S MedanKazuyoshi Taya
Mar 15, 2005·The Journal of Reproduction and Development·Toshiro TakedomiKazuyoshi Taya
Jun 8, 2006·The Journal of Reproduction and Development·Kazuaki SasakiKazuyoshi Taya
Nov 18, 2015·Animal Reproduction Science·Leyan YanZhendan Shi
Apr 27, 2004·The Journal of Veterinary Medical Science·Toru TakahashiKazuyoshi Hashizume
Mar 20, 2004·Biology of Reproduction·Harumichi IshigameKazuyoshi Taya
Mar 17, 2012·Biology of Reproduction·Monika A Ward
Sep 22, 2000·The Journal of Clinical Endocrinology and Metabolism·G W MontgomeryN G Martin

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