PMID: 9187944May 1, 1995Paper

Ovarian stimulation and ovarian tumours: a critical reappraisal

Human Reproduction Update
B C TarlatzisS Mantalenakis

Abstract

Increased interest has arisen recently about the possible association between ovarian stimulation and ovarian tumours. In this article, the current knowledge on the epidemiology, pathogenesis and aetiology of ovarian tumours is extensively reviewed in relation to the existing literature on the relationship between ovulation induction and ovarian neoplasia. The available data from epidemiological studies and case reports do not support a direct causal relationship between ovarian stimulation and ovarian cancer. However, it is possible that ovarian stimulants may have an augmenting role for special categories of tumours, e.g. sex-cord stromal tumours. A definite answer to this important issue may be reached through large prospective epidemiological studies or large retrospective well-designed case-control studies.

Citations

Apr 13, 2002·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Renato BaumanAsim Kurjak
Aug 30, 2000·Molecular and Cellular Endocrinology·B K CampbellD T Baird
May 7, 2004·Current Opinion in Obstetrics & Gynecology·Ri-Cheng ChianSeang-Lin Tan
Nov 1, 1996·Biological Reviews of the Cambridge Philosophical Society·W J Murdoch
Feb 1, 1997·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·P G ArtiniA R Genazzani
Dec 22, 1999·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·D GrochowskiM Szamatowicz
Aug 17, 2005·Reproductive Biomedicine Online·Chinmoy K Bose
Dec 4, 2003·Annals of the New York Academy of Sciences·N S Macklon, B C J M Fauser
Nov 3, 2009·Best Practice & Research. Clinical Obstetrics & Gynaecology·Grigoris F Grimbizis, Basil C Tarlatzis
Aug 15, 2013·The Cochrane Database of Systematic Reviews·Ivana RizzutoLesley A Smith
Jun 18, 2019·The Cochrane Database of Systematic Reviews·Ivana RizzutoLesley A Smith

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