Ovarian teratoma in children: a plea for collaborative clinical study

Journal of Ovarian Research
Justyna Łuczak, Maciej Bagłaj

Abstract

Although teratomas are the most common histologic subtype of childhood ovarian germ cell tumors, their appropriate treatment in this age group still remains unclear. Paucity of research dedicated exclusively to both mature and immature teratomas of the ovary, contribute to decision making difficulties. Therefore, we decided to review retrospectively our experience in treatment of pediatric ovarian teratomas in order to assess the epidemiology, presenting features, and diagnostic as well as surgical management of these lesions. The study comprised 58 patients. Fifty percent of patients were between 9 and 15 years old. Mature teratoma was diagnosed in 55(94.83%) patients, while 3(5.17%) patients presented with immature teratoma. Twenty eight (50.91%) girls with mature teratoma had laparotomy and 23 (41.82%) had laparoscopy performed as an initial operative approach. Ovarian tissue sparing technique (preservation of the ovarian tissue of the affected gonad) was applied in only 11.11% of patients operated in the first study period (years 1999-2003) and increased to 40.54% in the second half of our study (years 2004-2016). The extent of gonadal resection was not related with the size of the lesion. Bilateral lesions were noted in 8 ...Continue Reading

References

Jan 1, 1990·AJR. American Journal of Roentgenology·C L Sisler, M J Siegel
Oct 1, 1994·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·D M O'Connor, H J Norris
Feb 26, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·A AyhanA Ayhan
Jan 10, 2002·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Hiroyuki YanaiTadashi Yoshino
Mar 16, 2004·Journal of Pediatric Surgery·D BillmireUNKNOWN Children's Oncology Group (COG)
Mar 12, 2005·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Thomas M Ulbright
Jun 11, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jillian R MannUNKNOWN UK Children's Cancer Study Group Experience
Nov 26, 2009·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Mohammed O S Alotaibi, Oscar M Navarro
Jan 29, 2010·Journal of Pediatric Surgery·Sarah C OltmannAnne Fischer
Mar 10, 2011·Pediatrics and Neonatology·Tzu-Chun TsaiHan-Ping Wu
Jul 14, 2011·Journal of Pediatric and Adolescent Gynecology·Kathleen E O'Neill, Amber R Cooper
Dec 12, 2012·Pediatric Surgery International·Rahşan ÖzcanCenk Büyükünal
Jan 8, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Deborah F BillmireA Lindsay Frazier
Jan 21, 2014·Journal of Pediatric Surgery·Jonathan C PapicCharles M Leys
Feb 25, 2014·Journal of Pediatric and Adolescent Gynecology·Erin M RogersLisa Allen
Mar 25, 2014·Journal of Pediatric and Adolescent Gynecology·Erin M RogersSari Kives
Apr 15, 2014·Journal of Pediatric Surgery·Seppo TaskinenMervi Taskinen
Oct 7, 2014·International Journal of Women's Health·Noam Smorgick, Ron Maymon
Dec 3, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A Lindsay FrazierJames C Nicholson
Aug 25, 2015·Journal of Pediatric and Adolescent Gynecology·Yasmine YousefSherif Emil
Apr 22, 2016·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Jeong-Yeol ParkJoo-Hyun Nam
Jul 1, 2016·Pediatric Surgery International·Shaoguang FengXiaoming Chen
Nov 3, 2016·Annals of Oncology : Official Journal of the European Society for Medical Oncology·G MangiliG Ferrandina

❮ Previous
Next ❯

Citations

Feb 2, 2020·Cancer Metastasis Reviews·Justyna ŁuczakPiotr Dryjański
Jan 3, 2021·Pediatrics in Review·Cory TempletonJulie S W Childers
Jun 10, 2019·Gynecologic Oncology·Jenny L FrazerMatthew J Murray
Mar 2, 2021·The Journal of International Medical Research·Peng Zhu, Xiao-Yan Li
Jul 14, 2021·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Claudio SpinelliPierluigi Lelli Chiesa
Jul 8, 2021·Medicine·Dana-Teodora Anton-PăduraruElena Hanganu
Aug 1, 2021·Pediatric Blood & Cancer·David KielyNigel Hall
Jan 12, 2022·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·Sarah Braungart, Charlotte Victoria Smith

❮ Previous
Next ❯

Methods Mentioned

BETA
dissection
biopsy
biopsies

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Gynaecological Oncology
A AyhanG Ozbay
International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
Jonathan D BlackElena Ratner
Pediatric Surgery International
A J Jawad, A Al-Meshari
© 2022 Meta ULC. All rights reserved