Ovarian tissue cryopreservation and transplantation in patients with cancer

Obstetrics & Gynecology Science
Sooyoung KimTak Kim

Abstract

Chemotherapy and radiotherapy improved survival rates of patients with cancer. However, they can cause ovarian failure and infertility in women of reproductive age. Infertility following cancer treatment is considered a major quality of life issue. Ovarian tissue cryopreservation and transplantation is an important option for fertility preservation in adult patients with cancer who need immediate chemotherapy or do not want to undergo ovarian stimulation. Ovarian tissue freezing is the only option for preserving the fertility of prepubertal patients with cancer. In a recent review, it was reported that frozen-thawed ovarian transplantation has lead to about 90 live births and the conception rate was about 30%. Endocrine function recovery was observed in 92.9% between 3.5 and 6.5 months after transplantation. Based on our review, ovarian tissue cryopreservation and transplantation may be carefully considered before cancer treatment in order to preserve fertility and endocrine function in young cancer survivors.

References

Jan 29, 1999·Endocrinology and Metabolism Clinics of North America·S Howell, S Shalet
Jul 6, 2000·The New England Journal of Medicine·K Oktay, G Karlikaya
Jan 13, 2001·Molecular and Cellular Endocrinology·D Meirow
Sep 27, 2001·JAMA : the Journal of the American Medical Association·K OktayZ Rosenwaks
Dec 1, 2001·Human Reproduction Update·D Meirow, D Nugent
Apr 12, 2002·Genomics·Diana LuciferoJacquetta M Trasler
Jan 15, 2003·Human Reproduction·W H B WallaceT W Kelsey
Feb 27, 2003·Biology of Reproduction·Fujio MigishimaMinesuke Yokoyama
Jul 10, 2003·Fertility and Sterility·K Paul KatayamaEd Stehlik
Nov 10, 2004·Fertility and Sterility·Belen Martinez-MadridJacques Donnez
Dec 14, 2004·Fertility and Sterility·Ariel RevelAmir Arav
Mar 24, 2005·Journal of the National Cancer Institute. Monographs·Charles Sklar
Mar 24, 2005·Journal of the National Cancer Institute. Monographs·Hilary O D Critchley, W Hamish B Wallace
Apr 7, 2005·The Lancet Oncology·W Hamish B WallaceD Stewart Irvine
May 5, 2005·Current Opinion in Obstetrics & Gynecology·Emre Seli, Jacob Tangir
Jun 7, 2005·International Journal of Radiation Oncology, Biology, Physics·W Hamish B WallaceTom W Kelsey
Jun 9, 2005·The New England Journal of Medicine·Sherman J SilberRoger G Gosden
Feb 1, 2006·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Simone MarnitzWolfgang Hinkelbein
Feb 24, 2006·The Journal of Clinical Endocrinology and Metabolism·Wassim ChemaitillyCharles A Sklar
Mar 31, 2006·Pediatric Blood & Cancer·Tress GoodwinGary V Dahl
May 3, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Stephanie J LeeUNKNOWN American Society of Clinical Oncology
Jun 24, 2006·Reproductive Biomedicine Online·Gábor Vajta, Zsolt Péter Nagy
Mar 30, 2007·The New England Journal of Medicine·Sherman J Silber, Roger G Gosden
May 24, 2007·Tissue Engineering·Min XuTeresa K Woodruff
Jul 8, 2008·Human Reproduction·Claus Yding AndersenErik Ernst
Aug 12, 2008·Fertility and Sterility·Anne-Sophie Van EyckJacques Donnez
Oct 31, 2008·Current Opinion in Endocrinology, Diabetes, and Obesity·Dror Meirow
Dec 17, 2008·The New England Journal of Medicine·Sherman J SilberRoger G Gosden
Mar 25, 2009·International Journal of Radiation Oncology, Biology, Physics·Jennifer Y Wo, Akila N Viswanathan

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Citations

Jun 13, 2019·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Petra VukovićLidija Beketić-Orešković
Jul 11, 2019·International Journal of Molecular Sciences·Sanghoon LeeTak Kim
Jun 23, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Jessica Lauren FloydTerri Woodard
Jul 21, 2020·Cell Transplantation·Konstantinos SfakianoudisMara Simopoulou
Aug 23, 2019·Clinical Medicine Insights. Reproductive Health·Laura LotzMatthias W Beckmann
Nov 30, 2019·Current Treatment Options in Oncology·Lorenzo RossiOlivia Pagani
Oct 22, 2019·Post Reproductive Health·Dani Singer
Mar 1, 2019·Reproduction : the Official Journal of the Society for the Study of Fertility·Song LiQingxue Zhang
Jan 28, 2021·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Maria Luís SantosTeresa Almeida Santos
Oct 25, 2020·International Journal of Molecular Sciences·Hyun-Woong ChoTak Kim
Mar 17, 2021·Journal of Assisted Reproduction and Genetics·Lotte EijkenboomRonald Peek
Jul 16, 2021·Reproductive Medicine and Biology·Genia RozenCatharyn Stern
Jul 25, 2021·International Journal of Molecular Sciences·Seongmin KimTak Kim

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Methods Mentioned

BETA
hysterectomy
biopsies

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