Over 8 years experience on severe acute poisoning requiring intensive care in Hong Kong, China

Human & Experimental Toxicology
Sin-Man LamWing-Wa Yan

Abstract

In order to obtain up-to-date information on the pattern of severe acute poisoning and the characteristics and outcomes of these patients, 265 consecutive patients admitted to an intensive care unit in Hong Kong for acute poisoning from January 2000 to May 2008 were studied retrospectively. Benzodiazepine (25.3%), alcohol (23%), tricyclic antidepressant (17.4%), and carbon monoxide (15.1%) were the four commonest poisons encountered. Impaired consciousness was common and intubation was required in 67.9% of admissions, with a median duration of mechanical ventilation of less than 1 day. The overall mortality was 3.0%. Among the 257 survivors, the median lengths of stay in the intensive care unit and acute hospital (excluding days spent in psychiatric ward and convalescent hospital) were less than 1 day and 3 days, respectively. Factors associated with a longer length of stay included age of 65 or older, presence of comorbidity, Acute Physiology and Chronic Health Evaluation II score of 25 or greater, and development of shock, rhabdomyolysis, and aspiration pneumonia, while alcohol intoxication was associated with a shorter stay. This is the largest study of its kind in the Chinese population and provided information on the patte...Continue Reading

References

Dec 1, 1992·Toxicology Letters·S NoguéE Civeira
Jan 4, 1993·The Medical Journal of Australia·A HendersonS M Pond
Jun 11, 1993·Deutsche medizinische Wochenschrift·S Fürst, W Habscheid
Nov 10, 2000·Lancet·I R Edwards, J K Aronson
Oct 19, 2001·Deutsche medizinische Wochenschrift·A ViertelH R Brodt
Mar 7, 2002·Archives of General Psychiatry·Dominic LeePaul Yip
Mar 12, 2003·Chest·Babak MokhlesiThomas C Corbridge
Jan 7, 2004·Critical Care Medicine·Geoffrey K IsbisterIan M Whyte
Nov 17, 2005·JAMA : the Journal of the American Medical Association·Terje R PedersenIncremental Decrease in End Points Through Aggressive Lipid Lowering (IDEAL) Study Group
Dec 2, 2005·Clinical Trials : Journal of the Society for Clinical Trials·Paul M PalevskyMark W Smith
Jul 11, 2006·Intensive Care Medicine·Andreas ChristChristian Mueller
Nov 7, 2007·Human & Experimental Toxicology·Shahin ShadniaMohammad Abdollahi

Citations

Dec 10, 2013·Journal of Forensic Sciences·Jingshuo ZhangMin Shen
Oct 22, 2013·Basic & Clinical Pharmacology & Toxicology·Philippe PommierMaignan Maxime
Jul 14, 2017·Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists·Vinit AthavaleRavindranath Tiruvoipati
Oct 20, 2017·Journal of Community Hospital Internal Medicine Perspectives·Jose OrsiniElie Jean
Mar 4, 2014·Critical Care Medicine·Raya BrandenburgDylan W de Lange
Sep 25, 2019·Substance Abuse : Research and Treatment·Kelly L CervellioneCraig Thurm
Feb 5, 2020·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Alexander ReisingerGerald Hackl
May 20, 2014·Critical Care Medicine·Brendan James ClarkMarc Moss
Aug 5, 2020·Nursing in Critical Care·Adam WedinAngelica Forsberg
May 10, 2017·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Lauri KoskelaJanne Liisanantti
Oct 14, 2018·BMC Pharmacology & Toxicology·Aleksandra ŚwiderskaJacek Sein Anand

Related Concepts

Alcoholic Intoxication
Poisoning, Illuminating Gas
Intensive Care Unit
Hospital Stay
Transcription, Medical
Poisoning
Retrospective Studies
Suicide
Surgical Intensive Care
Age Distribution

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