Over-expression of CYP6A2 is associated with spirotetramat resistance and cross-resistance in the resistant strain of Aphis gossypii Glover

Pesticide Biochemistry and Physiology
Tianfei PengQingli Shang

Abstract

A laboratory-selected spirotetramat-resistant strain (SR) of cotton aphid developed 579-fold and 15-fold resistance to spirotetramat in adult aphids and 3rd instar nymphs, respectively, compared with a susceptible strain (SS) [26]. The SR strain developed high-level cross-resistance to alpha-cypermethrin and bifenthrin and very low or no cross-resistance to the other tested insecticides. Synergist piperonyl butoxide (PBO) dramatically increased the toxicity of spirotetramat and alpha-cypermethrin in the resistant strain. RT-qPCR results demonstrated that the transcriptional levels of CYP6A2 increased significantly in the SR strain compared with the SS strain, which was consistent with the transcriptome results [30]. The depletion of CYP6A2 transcripts by RNAi also significantly increased the sensitivity of the resistant aphid to spirotetramat and alpha-cypermethrin. These results indicate the possible involvement of CYP6A2 in spirotetramat resistance and alpha-cypermethrin cross-resistance in the cotton aphid. These together with other cross-resistance results have implications for the successful implementation of resistance management strategies for Aphis gossypii.

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Oct 11, 2015·Pesticide Biochemistry and Physiology·Yiou PanQingli Shang

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Citations

Apr 17, 2016·Environmental Science and Pollution Research International·Xiaojun ChenChunliang Lu
Feb 19, 2016·Pest Management Science·Xiu-Dao YuLan-Qin Xia
Dec 16, 2016·Viruses·Surapathrudu Kanakala, Murad Ghanim
Feb 1, 2017·Pest Management Science·Costas Ch VoudourisJohn T Margaritopoulos
Jun 17, 2020·Bulletin of Entomological Research·John T MargaritopoulosJ A Tsitsipis
Feb 15, 2017·Archives of Insect Biochemistry and Physiology·Abdelaziz KishkNabil Killiny
Sep 25, 2019·International Journal of Molecular Sciences·Yiou PanQingli Shang
Aug 23, 2020·Insects·Ritesh G JainNeena Mitter
Apr 12, 2021·Pesticide Biochemistry and Physiology·Dries AmezianGaëlle Le Goff
May 21, 2021·Journal of Agricultural and Food Chemistry·Xiaochun ZengQingli Shang
Nov 8, 2018·Journal of Agricultural and Food Chemistry·Xiaojun ChenYizhong Yang
Aug 28, 2021·Pesticide Biochemistry and Physiology·Gerald B WatsonThomas C Sparks

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