Over-suppression of bone turnover: does it exist?

Current Osteoporosis Reports
Juliet Compston

Abstract

Bone-turnover suppression is central to the therapeutic benefit of many interventions used to prevent osteoporotic fractures. There are theoretical concerns that long-term suppression may have adverse effects on bone strength, although at present no direct evidence exists that this happens. Nevertheless, further research is required to establish the optimal duration of treatment with antiresorptive agents.

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Mar 31, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D J LeemingM A Karsdal
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Oct 12, 2010·Expert Opinion on Biological Therapy·Kim HenriksenMorten Asser Karsdal

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