Overall gestational weight gain mediates the relationship between maternal and child obesity

BMC Public Health
Michele J JoseyClarLynda Williams-DeVane

Abstract

Approximately 17% of children in the U.S. are obese. Children that are overweight or obese are also more likely to be obese as adults and suffer from various chronic diseases and premature death. Maternal obesity can affect the weight status of her offspring through intrauterine mechanisms like excessive gestational weight gain (GWG). Current literature shows a positive association between maternal weight status and GWG on child obesity, yet the direct and indirect effects have not been decomposed or quantified. The purpose of this study was to estimate the effect of maternal obesity on child obesity, mediated by GWG, which is a modifiable risk factor. The study participants were a birth cohort of offspring from women who received prenatal care in the Duke/Durham Regional health care system in Durham, NC between 2005 and 2009. Anthropomorphic data was collected via electronic medical records (EMRs) during each voluntary visit to a health care facility. The exposure of interest was maternal obesity, measured by pre-pregnancy body mass index, the mediator was GWG, dichotomized into excessive and not excessive based on maternal prenatal BMI, and the outcome was child obesity at age 4, measured as BMI z-scores from the last recorde...Continue Reading

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Citations

May 30, 2020·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Elizabeth J TaylorNisreen A Alwan
Jul 10, 2020·Prenatal Diagnosis·Sezen KislalAndrea G Edlow
Oct 1, 2020·Pediatric Obesity·Stephanie V WrottesleyShane A Norris
Mar 25, 2020·BMJ Open Sport & Exercise Medicine·Ilena BauerHubert Preissl
Apr 30, 2021·Breastfeeding Medicine : the Official Journal of the Academy of Breastfeeding Medicine·Jennifer M MaskarinecSarah A Keim
May 15, 2021·Current Obesity Reports·Veronica R JohnsonFatima Cody Stanford
Jun 4, 2021·American Journal of Perinatology·William A GrobmanUNKNOWN NICHD nuMoM2b NHLBI nuMoM2b Heart Health Study Networks
Oct 21, 2020·Women and Birth : Journal of the Australian College of Midwives·Madeleine R BentonJodie M Dodd
Dec 1, 2021·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Jerod M RasmussenPathik D Wadhwa

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