Overall survival time prediction for high-grade glioma patients based on large-scale brain functional networks

Brain Imaging and Behavior
Luyan LiuDinggang Shen

Abstract

High-grade glioma (HGG) is a lethal cancer with poor outcome. Accurate preoperative overall survival (OS) time prediction for HGG patients is crucial for treatment planning. Traditional presurgical and noninvasive OS prediction studies have used radiomics features at the local lesion area based on the magnetic resonance images (MRI). However, the highly complex lesion MRI appearance may have large individual variability, which could impede accurate individualized OS prediction. In this paper, we propose a novel concept, namely brain connectomics-based OS prediction. It is based on presurgical resting-state functional MRI (rs-fMRI) and the non-local, large-scale brain functional networks where the global and systemic prognostic features rather than the local lesion appearance are used to predict OS. We propose that the connectomics features could capture tumor-induced network-level alterations that are associated with prognosis. We construct both low-order (by means of sparse representation with regional rs-fMRI signals) and high-order functional connectivity (FC) networks (characterizing more complex multi-regional relationship by synchronized dynamics FC time courses). Then, we conduct a graph-theoretic analysis on both networ...Continue Reading

References

Oct 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·B BiswalJ S Hyde
Oct 17, 1998·Journal of the National Cancer Institute·J G CairncrossD N Louis
Mar 24, 2000·Cerebral Cortex·C CavadaF Reinoso-Suárez
Oct 16, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M KleinN K Aaronson
Mar 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Roger StuppSerge Leyvraz
Jun 20, 2003·NeuroImage·Barry Horwitz
Jan 28, 2004·Journal of Neurosurgery·Marcos V C MaldaunRaymond Sawaya
Jun 26, 2004·Science·György Buzsáki, Andreas Draguhn
Sep 8, 2004·Trends in Cognitive Sciences·Olaf SpornsClaus C Hilgetag
Mar 19, 2005·Journal of Neurology, Neurosurgery, and Psychiatry·A R GiovagnoliA Boiardi
Jun 1, 2005·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Stanley S StylliPriya Rajendra
Jun 16, 2005·NeuroImage·John Ashburner, Karl J Friston
Feb 3, 2006·Cerebral Cortex·C J StamPh Scheltens
Jul 25, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Fabrice BartolomeiCornelis J Stam
Nov 24, 2006·Brain : a Journal of Neurology·Michel DesmurgetHugues Duffau
Mar 30, 2007·Brain : a Journal of Neurology·Ingrid R OlsonYoussef Ezzyat
Jul 10, 2007·Acta Neuropathologica·David N LouisPaul Kleihues
Sep 1, 2007·NeuroImage·John Ashburner
Oct 20, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Wei ChenTimothy Cloughesy
Dec 7, 2007·Magnetic Resonance Imaging·Michal MiklPetr Krupa
Mar 8, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Justin S SmithMitchel S Berger
Feb 5, 2009·Nature Reviews. Neuroscience·Ed Bullmore, Olaf Sporns
Sep 25, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Bernard W Balleine, John P O'Doherty
Oct 13, 2009·NeuroImage·Mikail Rubinov, Olaf Sporns
Dec 29, 2009·NeuroImage·Andrew ZaleskyEdward T Bullmore
Apr 8, 2010·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Stuart A GrossmanUNKNOWN NABTT CNS Consortium
May 18, 2010·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Martijn P van den Heuvel, Hilleke E Hulshoff Pol
Jul 16, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Mary-Ellen LynallEd Bullmore
Sep 8, 2010·NeuroImage·Stephen M SmithMark W Woolrich
Sep 28, 2010·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·H WangP Van Mieghem
Oct 1, 2010·Journal of Magnetic Resonance Imaging : JMRI·Sona SaksenaTom Mikkelsen
Jun 15, 2011·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Cristina Rosazza, Ludovico Minati

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Citations

Jun 14, 2021·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Quinlan D BuchlakMassimo Piccardi

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Methods Mentioned

BETA
imaging techniques
SMA
imaging technique
biopsy
feature extraction
total resection

Software Mentioned

GRETNA
SPM
fMRI
SPM8
BrainNet Viewer
LASSO

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