Overcoming diabetic gastroparesis en route to kidney transplant

Clinical Transplantation
John de CsepelKhalid Butt

Abstract

Gastroparesis is a debilitating condition that affects a significant number of diabetic patients. Some of these patients have end-stage renal disease and are in need of kidney transplant. Symptoms of gastroparesis include: early satiety, pyrosis, epigastric pain, nausea and vomiting, which may lead to caloric and electrolyte deficiencies as well as significant weight loss. A viable option for diabetic gastroparesis patients who fail first line treatments consisting of dietary changes and gastric prokinetic medications is gastric electrical stimulator (GES) implantation. We present a 41-yr-old man and 35-yr-old woman with diabetic gastroparesis, who were initially deemed unacceptable candidates for renal transplantation because of marked malnourishment and a concern that they would not be able to tolerate immunosuppressant medications. In less than two yr following GES implantation, each patient underwent a successful kidney transplant.

References

Dec 1, 2001·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·D Cohen, C Galbraith
Jul 16, 2003·Gastroenterology Clinics of North America·D Scott SmithChristopher D Ferris
Aug 2, 2003·Gastroenterology·Thomas AbellWarren Starkebaum
Dec 16, 2003·American Journal of Surgery·Jameson ForsterRichard W McCallum

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Citations

Nov 11, 2018·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Sanja Klobučar MajanovićDavor Štimac

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