Overcommitment to work is associated with changes in cardiac sympathetic regulation

Psychosomatic Medicine
T G VrijkotteEco J C de Geus

Abstract

Work stress is associated with an increased risk for cardiovascular disease (CVD). Exaggerated cardiovascular reactivity to work-related stressors or incomplete recovery after work is a proposed mechanism underlying this increase in risk. This study examined the effects of work stress on 24-hour profiles of the pre-ejection period (PEP), a measure of cardiac sympathetic activity, obtained from ambulatory measurement of the impedance cardiogram. A total of 67 male white-collar workers (age 47.1 +/- 5.2) underwent ambulatory monitoring on 2 workdays and 1 non-workday. Work stress was defined according to Siegrist's model as 1) a combination of high effort and low reward at work (high imbalance) or 2) an exhaustive work-related coping style (high overcommitment). High overcommitment was associated with shorter absolute PEP levels during all periods on all 3 measurement days, reduced wake-to-sleep PEP differences and reduced PEP variability, as indexed by the SD. Overcommitment to work was associated with an increase in basal sympathetic drive and a reduction in the dynamic range of cardiac sympathetic regulation. Both findings are compatible with the hypothesis that overcommitment induces beta-receptor down-regulation.

References

Nov 1, 1979·Psychophysiology·D B Newlin, R W Levenson
Dec 1, 1992·Journal of Psychosomatic Research·P R Falger, E G Schouten
Jan 1, 1990·Psychophysiology·A SherwoodL J van Doornen
Nov 1, 1990·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·A SherwoodJ A Blumenthal
Jan 1, 1990·Psychophysiology·R M Kelsey, W Guethlein
Jan 1, 1989·Annals of Biomedical Engineering·J J SmithT J Ebert
Jan 1, 1989·Psychophysiology·L J van Doornen, E J de Geus
Apr 1, 1986·Acta Physiologica Scandinavica·J SvedenhagP Hjemdahl
Jul 1, 1988·European Heart Journal·A Appels, P Mulder
Sep 27, 1984·The New England Journal of Medicine·M R Bristow
Dec 1, 1983·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·Y MiyamotoT Mikami
Jan 1, 1982·Cardiology·G F LeviM Basagni
Jul 1, 1995·Occupational and Environmental Medicine·A J van der BeekS Kuiper
Jul 1, 1994·Psychosomatic Medicine·J E DimsdaleE Dillon
Jan 1, 1994·Annual Review of Public Health·P L SchnallD Baker
Sep 1, 1996·Circulation·L M Buja
Mar 1, 1996·Psychophysiology·G H WillemsenD Carroll
Jan 15, 1998·The New England Journal of Medicine·B S McEwen
Apr 18, 1998·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·K C LightM T Allen
Aug 26, 1998·Progress in Cardiovascular Diseases·J Joseph, E M Gilbert
Dec 8, 1998·Journal of Applied Physiology·A SherwoodJ S Hutcheson
Mar 17, 1999·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·E S MezzacappaE S Katkin
Jun 24, 1999·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·B H YuP J Mills
Dec 11, 1999·Psychosomatic Medicine·T G VrijkotteE J de Geus
Jan 29, 2000·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·B S McEwen
May 20, 2000·Journal of Applied Physiology·G Cybulski
Sep 12, 2000·Current Hypertension Reports·P Palatini, S Julius
Nov 18, 2000·Hypertension·G Mancia, G Parati
Sep 27, 2001·Psychosomatic Medicine·H SchächingerW Langewitz
Oct 19, 2002·BMJ : British Medical Journal·Mika KivimäkiJuhani Kirjonen
Jun 5, 2003·Medicine and Science in Sports and Exercise·Kimberly A BrownleyKathleen C Light
Nov 1, 2003·Behavior Research Methods, Instruments, & Computers : a Journal of the Psychonomic Society, Inc·Harriëtte RieseEco J C de Geus

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Citations

Sep 14, 2010·Journal of Empirical Research on Human Research Ethics : JERHRE·Brian C MartinsonMelissa S Anderson
Jul 20, 2006·Nursing Research·Monica J E Parry, Judith McFetridge-Durdle
Nov 13, 2012·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·René van LienEco J C de Geus
Dec 8, 2015·American Journal of Human Biology : the Official Journal of the Human Biology Council·Jason A DeCaro
Dec 21, 2005·Psychophysiology·Jan H HoutveenEco J C Geus
Dec 15, 2010·Psychophysiology·Melike M FourieKevin G F Thomas
Aug 16, 2014·Psychophysiology·René van LienEco J C de Geus
Oct 15, 2005·Biological Psychology·Annebet D GoedhartEco J C de Geus
Sep 25, 2014·International Archives of Occupational and Environmental Health·Jennifer L GarzaJack T Dennerlein
Jun 22, 2010·Biological Psychology·Ydwine Jieldouw Zanstra, Derek William Johnston
Sep 29, 2007·Biological Psychology·Jan H Houtveen, Lorenz J P van Doornen
Apr 23, 2016·International Journal of Environmental Research and Public Health·Johannes Siegrist, Jian Li
Feb 20, 2020·Stress and Health : Journal of the International Society for the Investigation of Stress·Ruben TinajeroYana Suchy
Apr 5, 2013·The Journal of Clinical Endocrinology and Metabolism·Carmilla M M LichtBrenda W J H Penninx
Feb 3, 2021·Journal of the American Heart Association·Lisette M HarteveldUNKNOWN FemNAT‐CD collaborators *
Nov 22, 2020·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·T G M VrijkotteJ A Bosch

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