Overcrowding-mediated stress alters cell proliferation in key neuroendocrine areas during larval development in Rhinella arenarum

Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology
Mijal J DistlerAndrea G Pozzi

Abstract

Exposure to adverse environmental conditions can elicit a stress response, which results in an increase in endogenous corticosterone levels. In early life stages, it has been thoroughly demonstrated that amphibian larval growth and development is altered as a consequence of chronic stress by interfering with the metamorphic process, however, the underlying mechanisms involved have only been partially disentangled. We examined the effect of intraspecific competition on corticosterone levels during larval development of the toad Rhinella arenarum and its ultimate effects on cell proliferation in particular brain areas as well as the pituitary gland. While overcrowding altered the number of proliferating cells in the pituitary gland, hypothalamus, and third ventricle of the brain, no differences were observed in areas which are less associated with neuroendocrine processes, such as the first ventricle of the brain. Apoptosis was increased in hypothalamic regions but not in the pituitary. With regards to pituitary cell populations, thyrotrophs but not somatoatrophs and corticotrophs showed a decrease in the cell number in overcrowded larvae. Our study shows that alterations in growth and development, produced by stress, results fro...Continue Reading

References

Mar 1, 1975·Endocrinology·C Gomez-SanchezN M Kaplan
Sep 27, 2000·Proceedings of the National Academy of Sciences of the United States of America·V LemaireD N Abrous
Dec 26, 2001·The Journal of Experimental Zoology·Karen Ann Glennemeier, Robert John Denver
Aug 6, 2002·General and Comparative Endocrinology·Karen Ann Glennemeier, Robert John Denver
Sep 25, 2002·General and Comparative Endocrinology·L Michael Romero
Mar 5, 2003·Hormones and Behavior·Ignacio T Moore, Tim S Jessop
Jan 28, 2004·Cell·Nika N Danial, Stanley J Korsmeyer
Aug 3, 2005·General and Comparative Endocrinology·Daniela Denari, Nora R Ceballos
Sep 6, 2005·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Erica J Crespi, Robert J Denver
Oct 26, 2005·Neuroscience·D L A Van den HoveC E Blanco
Sep 8, 2006·Neuroreport·Tomoya KawamuraDaiichiro Nakahara
May 9, 2007·The International Journal of Developmental Biology·Quincy A Quick, Elba E Serrano
Oct 17, 2008·Nature·Vaishnav Krishnan, Eric J Nestler
Nov 4, 2008·Brain Research·Tatiane S C CamozzatoAldo B Lucion
Dec 6, 2008·Developmental Biology·Robert J DenverJ David Furlow
Jul 15, 2009·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Andrew K Davis, John C Maerz
Jan 26, 2013·Current Topics in Developmental Biology·Robert J Denver
Dec 3, 2014·Psychoneuroendocrinology·En-Ju D LinMatthew J During
Feb 14, 2015·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Robin W Warne, Erica J Crespi
Jun 24, 2015·The Journal of Endocrinology·Barry N MadisonNicholas J Bernier

❮ Previous
Next ❯

Citations

Sep 11, 2016·General and Comparative Endocrinology·P S Kulkarni, N P Gramapurohit

❮ Previous
Next ❯

Related Concepts

Related Feeds

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Related Papers

Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology
Robin W Warne, Erica J Crespi
Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology
Brian D KearneyRichard D Reina
Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology
Nicole PerfitoGeorge E Bentley
Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution
Robert P AranRonald M Bonett
© 2021 Meta ULC. All rights reserved