Overdiagnosis or not? 2017 ACC/AHA high blood pressure clinical practice guideline: Consequences of intellectual conflict of interest

Journal of General and Family Medicine
Kei Miyazaki

Abstract

American Heart Association/the American College of Cardiology and nine other professional organizations have issued a new hypertension clinical practice guideline (CPG) on November 2017, which has lowered the hypertension threshold to 130/80 mmHg. American Academy of Family Medicine has decided to not endorse this new CPG for various reasons including flaws in CPG development process and a limited additional benefit for lower treatment targets. The major concern was intellectual conflict of interest (COI). Substantial weight was given to SPRINT trial, which provided the basis for the recommended change in blood pressure targets. It is a serious intellectual COI that the Chair of the SPRINT trial steering committee was commissioned as chair of the guideline panel. The new threshold would lead to 46 percent of the U.S. adult population being categorized as having hypertension, while using the previous threshold that figure would be 32 percent. Should we call this change as overdiagnosis?

References

Sep 6, 2002·The New England Journal of Medicine·Norman G Levinsky
Apr 24, 2010·Journal of the National Cancer Institute·H Gilbert Welch, William C Black
May 19, 2010·Annals of Internal Medicine·Gordon GuyattHolger Schünemann
Apr 14, 2012·Journal of Clinical Epidemiology·Susan L NorrisRichard Deyo
Jun 5, 2013·Journal of Evaluation in Clinical Practice·Lisa CosgroveAllen F Shaughnessy
Dec 21, 2017·The New England Journal of Medicine

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Software Mentioned

GRADE of Assessment , Development and Evaluation )
SPRINT
GRADE

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