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Overexpression of Nrf2 attenuates Carmustine-induced cytotoxicity in U87MG human glioma cells

BMC Cancer

Mar 13, 2015

Sangeetha Sukumari-RameshKrishnan M Dhandapani

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Abstract

Malignant glioma is one of the most devastating tumors in adults with poor patient prognosis. Notably, glioma often exhibits resistance to conventional chemotherapeutic approaches, complicating patient treatments. However, the molecular mediators involved in tumor chemoresistance remain...read more

Mentioned in this Paper

Gene Expression
Flow Cytometry
GABPA gene
Oxidative Stress
Antineoplastic Agents
Disease Management
Glioma
2-tert-butylhydroquinone
Study
NF-E2-Related Factor 2
Paper Details
References
  • References45
  • Citations5
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Overexpression of Nrf2 attenuates Carmustine-induced cytotoxicity in U87MG human glioma cells

BMC Cancer

Mar 13, 2015

Sangeetha Sukumari-RameshKrishnan M Dhandapani

PMID: 25851054

DOI: 10.1186/s12885-015-1134-z

Abstract

Malignant glioma is one of the most devastating tumors in adults with poor patient prognosis. Notably, glioma often exhibits resistance to conventional chemotherapeutic approaches, complicating patient treatments. However, the molecular mediators involved in tumor chemoresistance remain...read more

Mentioned in this Paper

Gene Expression
Flow Cytometry
GABPA gene
Oxidative Stress
Antineoplastic Agents

Related Papers

Paper Details
References
  • References45
  • Citations5
12345

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