Overlapping clinical features of lupus and leptospirosis

Clinical Rheumatology
Cheryl Barnabe, Nicole Fahlman

Abstract

Systemic manifestations of infectious disease may be confused with systemic lupus erythematosus (SLE), leading to potential patient morbidity and mortality. We report the case of a patient with severe renal failure and liver involvement who was initially diagnosed and treated for leptospirosis infection. It was later determined that his organ involvement was related to active SLE. We review the clinical and laboratory features common to both SLE and leptospirosis infection to highlight not only the importance of maintaining a high index of suspicion for infectious organisms in a patient with a suspect travel history but also the recognition of atypical features of a systemic autoimmune disease.

References

Feb 15, 2003·The American Journal of Medicine·Pierre TattevinJérome Hoff
Apr 16, 2003·Annals of the Rheumatic Diseases·R A Asherson, R Cervera
Oct 25, 2003·Clinical Rheumatology·G PappasE Tsianos
Sep 3, 2005·The Australian Journal of Physiotherapy·S Dianne LiddleG David Baxter
Feb 2, 2006·Current Infectious Disease Reports·Jessica N Ricaldi, Joseph M Vinetz

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Citations

Oct 15, 2009·Annals of Tropical Medicine and Parasitology·S B CraigD B McKay
Feb 11, 2020·Oxford Medical Case Reports·Lotfollah DavoodiAlireza Razavi

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