Overnight or fresh buffy coat-derived platelet concentrates prepared with various platelet pooling systems

Transfusion
M J Dijkstra-TiekstraJ de Wildt-Eggen

Abstract

For logistic reasons, possibilities to produce both platelet (PLT) concentrates prepared from fresh or overnight-stored whole blood (fresh and o/n PCs, respectively) are convenient. The consequences of both possibilities are not well described. The PLT pooling system used might also influence the condition of PCs. Our aim was to compare fresh and o/n PCs with different PLT pooling systems. Fresh and o/n PCs were prepared from buffy coats and plasma in PLT pooling systems of Baxter, Fresenius, Terumo, or Pall (n = 5). PCs were stored for 9 days. The in vitro quality was determined by the PLT count, pH, glucose, lactate, pO(2), pCO(2), CD62P expression, and annexin V binding. The o/n PCs showed higher PLT count (approx. 460 x 10(9)/PC vs. approx. 310 x 10(9)/PC), pCO(2), and lactate concentration and lower pH, pO(2), glucose concentration, CD62P expression (until Day 5), and annexin V binding (until Day 7) compared with fresh PCs (p < 0.05). Only for o/n PCs in the Baxter and Fresenius systems did the pH and glucose concentration remain higher, and the lactate concentration and CD62P expression remained lower than that of o/n PCs in the Pall and Terumo systems. The pH for fresh PCs in the Baxter and Fresenius systems was more oft...Continue Reading

References

Aug 1, 1996·Journal of Cellular Physiology·F TablinJ H Crowe
May 1, 1997·Transfusion·J de Wildt-EggenH C van Prooijen

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Citations

Mar 16, 2013·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·M J Dijkstra-TiekstraJ de Wildt-Eggen
Sep 2, 2008·Transfusion clinique et biologique : journal de la Société française de transfusion sanguine·T ChakrounS Yacoub
Jul 24, 2008·Transfusion·Margriet J Dijkstra-TiekstraJanny de Wildt-Eggen
Feb 1, 2013·Transfusion·Effimia GkoumassiJanny de Wildt-Eggen
Jan 28, 2011·Transfusion·M J Dijkstra-TiekstraUNKNOWN Biomedical Excellence for Safer Transfusion Collaborative
Jan 15, 2015·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Margriet J Dijkstra-TiekstraJanny de Wildt-Eggen
Apr 1, 2015·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·J PhilipR S Mallhi
Nov 30, 2014·Transfusion Medicine Reviews·Pieter F van der Meer, Dirk de Korte
Dec 3, 2020·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Shashank OjhaMinal Poojary

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