Overuse of inhaled corticosteroids in COPD: five questions for withdrawal in daily practice

International Journal of Chronic Obstructive Pulmonary Disease
Didier CataldoWim Janssens

Abstract

Evidence and guidelines are becoming increasingly clear about imbalance between the risks and benefits of inhaled corticosteroids (ICSs) in patients with COPD. While selected patients may benefit from ICS-containing regimens, ICSs are often inappropriately prescribed with - according to Belgian market research data - up to 70% of patients in current practice receiving ICSs, usually as a fixed combination with a long-acting β2-adrenoreceptor agonist. Studies and recommendations support withdrawal of ICSs in a large group of patients with COPD. However, historical habits appear difficult to change even in the light of recent scientific evidence. We have built a collaborative educational platform with chest physicians and primary care physicians to increase awareness and provide guidance and support in this matter.

Citations

May 6, 2020·The European Respiratory Journal·James D ChalmersMarc Miravitlles
Sep 5, 2020·Expert Review of Clinical Pharmacology·Paola RoglianiLuigino Calzetta
Jun 6, 2020·Pharmaceutical Medicine·Alexander J K Wilkinson, Greg Anderson
Feb 3, 2021·Respiratory Medicine·P A TuranM Büyükşirin
Jan 7, 2021·International Journal of Chronic Obstructive Pulmonary Disease·Ji-Ho LeeWon-Yeon Lee
May 21, 2021·International Journal of Chronic Obstructive Pulmonary Disease·Ioanna TsiligianniRudi Peché
Jun 25, 2021·International Journal of Chronic Obstructive Pulmonary Disease·Miguel Roman-Rodriguez, Alan Kaplan
Oct 7, 2021·American Journal of Physiology. Lung Cellular and Molecular Physiology·Byron M ThomashowJames D Crapo

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