Overview of biological response modifiers.

Seminars in Surgical Oncology
E D StarenJ S Economou

Abstract

The immune system is regulated by a variety of lymphokines, monokines, and colony-stimulating factors. Most have now been cloned and it is clear that these cytokines have a broad range of overlapping immunological, inflammatory, and physiological properties. Some of these cytokines might favorably influence the biological therapy of cancer and they have been collectively referred to by clinicians as "biological response modifiers." This review summarizes current knowledge about the molecular biology and biological properties of most of the common cytokines and provides a brief survey of their therapeutic potential in patients with cancer.

References

Nov 8, 1985·Science·L J Old
Jun 5, 1987·Science·S C Clark, R Kamen
Jan 1, 1987·Annual Review of Immunology·W E Paul, J Ohara
Dec 1, 1987·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·W E Paul
Aug 1, 1988·The Journal of Experimental Medicine·P NawrothD Stern
Jun 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·K TakatsuA Tominaga
Apr 1, 1985·Immunology Today·G Trinchieri, B Perussia
Apr 1, 1986·Immunology Today·J M Garland
Jan 1, 1987·Immunology Today·S B Mizel
Feb 1, 1986·Immunology Today·J J OppenheimS K Durum
Jan 1, 1987·Immunology Today·S K Dower, D L Urdal

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Citations

Jul 1, 1994·Biulleten' eksperimental'noĭ biologii i meditsiny·V N BoĭkoS N Bykovskaia
Nov 1, 1991·Research in Microbiology·M DenisE O Gregg
Mar 3, 2004·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Eyal RussoSheldon L Kaplan
Dec 1, 1992·American Journal of Surgery·E A MannD L Kreutzer
Oct 1, 1996·Nuclear Medicine and Biology·J LiM L Thakur
Feb 1, 1992·Journal of Clinical Pathology·R C Rees
Dec 1, 1992·American Journal of Obstetrics and Gynecology·S WilliamsJ L Collins
Oct 1, 1991·Clinics in Dermatology·V RuoccoG Castello
May 1, 1997·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·P Hrelia, S Tanneberger
Jul 22, 2008·Hematology/oncology Clinics of North America·Marc Ian Barasch
May 20, 1999·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·G S Giebink
May 13, 2009·Clinical and Experimental Otorhinolaryngology·Steven K JuhnTina Huang
Sep 1, 1994·Annals of Surgical Oncology·A R MillerJ S Economou

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