Overview of Electrophysiological Techniques

Current Protocols in Pharmacology
Alan D Wickenden

Abstract

This unit provides an overview of the principal electrophysiological techniques commonly used for the study of ionic currents and the ion channels that mediate them. These techniques include electroencephalograms (EEGs), electrocardiograms (ECGs), single- and multiunit extracellular recording, multielectrode arrays, transepithelial recording, impedance measurements, and current-clamp, voltage-clamp, patch-clamp, and lipid bilayer recording. The unit also discusses recent advances in high-throughput, automated electrophysiological techniques for drug discovery and the use of stem cells as a tissue source.

References

Aug 1, 1988·The Journal of General Physiology·R Horn, A Marty
Mar 1, 1988·Journal of Neuroscience Methods·J L Novak, B C Wheeler
Aug 1, 1981·Pflügers Archiv : European journal of physiology·O P HamillF J Sigworth
Feb 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·R LatorreC Hidalgo
Feb 22, 2001·Science·J C VenterX Zhu
Mar 10, 2001·Nature·E S LanderUNKNOWN International Human Genome Sequencing Consortium
Apr 18, 2002·Biosensors & Bioelectronics·Kathryn G KlemicFred J Sigworth
Jul 12, 2003·Journal of Biomolecular Screening·Kirk SchroederJennings Worley
Apr 1, 1952·The Journal of Physiology·A L HODGKINB KATZ
Apr 1, 1952·The Journal of Physiology·A L HODGKIN, A F HUXLEY
Apr 1, 1952·The Journal of Physiology·A L HODGKIN, A F HUXLEY
Apr 1, 1952·The Journal of Physiology·A L HODGKIN, A F HUXLEY
Apr 14, 2004·Current Drug Targets. CNS and Neurological Disorders·R C Hogg, D Bertrand
Apr 20, 2004·Assay and Drug Development Technologies·A BrüggemannN Fertig
Oct 22, 2004·Nature·UNKNOWN International Human Genome Sequencing Consortium
Jan 27, 2005·Assay and Drug Development Technologies·Huimin TaoAndrea Ghetti
Mar 22, 2006·Expert Opinion on Therapeutic Targets·Chris Mathes
Apr 20, 2006·Biosensors & Bioelectronics·Qingjun LiuPing Wang
Jun 9, 2006·Journal of Biomolecular Screening·Alan FinkelJames Costantin
Mar 22, 2007·Expert Opinion on Therapeutic Targets·Cecilia FarreNiels Fertig
Jul 24, 2007·Experimental Neurology·Sebastian IllesMarcel Dihné
Sep 11, 2007·Drug Discovery Today·Peter SartipyJohan Hyllner
Mar 22, 2008·Nature Reviews. Drug Discovery·John DunlopRobert Arias
Apr 23, 2008·Current Protocols in Neuroscience·D V Madison, E B Edson
Apr 23, 2008·Current Protocols in Neuroscience·M B Jackson
Apr 23, 2008·Current Protocols in Neuroscience·G Stuart
Apr 23, 2008·Current Protocols in Neuroscience·M B Jackson
Apr 23, 2008·Current Protocols in Neuroscience·Michael Daw, John Isaac
May 31, 2008·Stem Cells and Development·Oren CaspiLior Gepstein
Oct 2, 2008·Methods in Molecular Biology·Michael FejtlAlbrecht Lepple-Wienhues
Jan 20, 2009·Combinatorial Chemistry & High Throughput Screening·Roger L Papke, Cathy Smith-Maxwell
Mar 24, 2009·FEBS Letters·Miroslava StastnaJennifer E Van Eyk
Oct 6, 2009·Current Protocols in Neuroscience·Ian G Campbell
Oct 6, 2009·Current Protocols in Neuroscience·C Martín del CampoMiguel A Cortez Freire
Feb 16, 2010·Journal of Pharmacological and Toxicological Methods·Shengde PengAndrew Bruening-Wright

❮ Previous
Next ❯

Citations

Feb 22, 2017·IEEE Transactions on Bio-medical Engineering·Chang Hao ChenTim C Lei
Aug 6, 2014·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Eric RöhnerGeorg Matziolis
Jun 28, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Maria TsemperouliKaori Sugihara

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Environmental Science & Technology
Current Protocols in Pharmacology
Alison ObergrussbergerNiels Fertig
Current Protocols in Bioinformatics
Lauren Mills
© 2021 Meta ULC. All rights reserved