PMID: 15218812Jun 29, 2004Paper

Overview of European pilot study of interferon beta-Ib in primary progressive multiple sclerosis

Multiple Sclerosis : Clinical and Laboratory Research
X Montalban

Abstract

This short monograph describes a trial of interferon beta-1b in patients with primary progressive multiple sclerosis (PPMS) or transitional MS. Designed as a randomized, placebo-controlled pilot, the trial randomly placed 73 eligible patients into two groups, placebo or interferon beta-1b 8 MIU given subcutaneously every other day for two years. Significant differences favouring interferon beta-1b in the MSFC score, T2 lesion volume and TI lesion volume at 24 months were observed. Further study of interferon beta-Ib therapy in PPMS patients in warranted.

Citations

Jun 14, 2008·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·A MillonigF Deisenhammer
May 12, 2010·International Journal of Clinical Practice·S Y Lim, C S Constantinescu
Feb 21, 2016·Clinical Neurology and Neurosurgery·R AlroughaniS Al-Shammri
Dec 2, 2004·Expert Opinion on Emerging Drugs·Clyde Markowitz
Nov 3, 2005·Expert Opinion on Emerging Drugs·Rachel FarrellGavin Giovannoni
Jan 1, 2014·Multiple Sclerosis and Related Disorders·K S PandeyF D Lublin
Aug 13, 2005·Pharmacology & Therapeutics·Oliver NeuhausHans-Peter Hartung
Sep 2, 2008·Expert Review of Neurotherapeutics·Albert Lo
Jul 20, 2010·Multiple Sclerosis : Clinical and Laboratory Research·K RejdakG Giovannoni
Mar 6, 2010·Multiple Sclerosis : Clinical and Laboratory Research·Z KhaleeliA J Thompson
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Jan 22, 2010·The Cochrane Database of Systematic Reviews·Juan Ignacio RojasEdgardo Cristiano
Apr 28, 2005·Expert Review of Neurotherapeutics·Jack Burks
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Jan 23, 2018·Multiple Sclerosis : Clinical and Laboratory Research·Xavier MontalbanFrauke Zipp
Oct 1, 2010·Continuum : Lifelong Learning in Neurology·Kathleen Hawker

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