Overview of high-risk HPV's 16 and 18 infected cervical cancer: pathogenesis to prevention

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
Sabitha RamakrishnanGaneshan Mathan

Abstract

As general, the Human papillomavirus (HPV) causes the most sexually transmitted diseases. Among well categorized 80 types, the high-risk types HPV's 16 and 18 are highly involved in 70% of cervical cancer. The virulence of HPV is mainly exhibited by E5, E6 and E7 encoded oncoproteins that cause low to high-grade cervical lesions (CIN-1, 2, 3), leading to form 99.7% of squamous cell and 89% of adenocarcinomas cervical cancer worldwide. This study mainly encircles the major role of E5, E6 and E7 oncoproteins in HPV 16 and 18. Further discussed the uprising of significant biomarkers and their cellular process in different stages of cervical cancer with current prevention and treatment regimens. Hence, this integration will evoke novel markers, potential vaccination and various treatments approaches with special reference for HPV16 and 18 infected cervical cancers.

References

Nov 15, 1995·Cancer·T W ParkT C Wright
Sep 15, 1996·Experimental Cell Research·K Zhang, R H Kramer
Mar 1, 1997·The Journal of Pathology·J M Walboomers, C J Meijer
Feb 10, 1999·The Journal of Infectious Diseases·C J LaceyJ S Roberts
Feb 1, 2000·Journal of Cellular Physiology·T Scholzen, J Gerdes
Jun 6, 2000·Experimental Cell Research·E Endl, J Gerdes
Apr 5, 2001·International Journal of Radiation Oncology, Biology, Physics·D K GaffneyM Dodson
Apr 6, 2001·International Journal of Cancer. Journal International Du Cancer·R KlaesM von Knebel Doeberitz
Jul 17, 2001·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·P BirnerG Oberhuber
Sep 19, 2001·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·K M HaasH Kosmehl
Sep 25, 2001·International Journal of Radiation Oncology, Biology, Physics·S NasuL Milas
Jan 31, 2002·Journal of Chromatography. B, Biomedical Sciences and Applications·T H Tsai
Apr 12, 2002·Lancet·Nubia MuñozUNKNOWN International Agency for Research on Cancer. Multicentric Cervical Cancer Study Group
Jun 5, 2002·Nature Reviews. Cancer·Harald zur Hausen
Nov 22, 2002·The New England Journal of Medicine·Laura A KoutskyUNKNOWN Proof of Principle Study Investigators
Feb 19, 2003·Nature Genetics·Michael NicolasFreddy Radtke
Aug 7, 2003·Journal of the National Cancer Institute·Denise Nardelli-HaefligerPierre De Grandi
Nov 6, 2003·Molecular Therapy : the Journal of the American Society of Gene Therapy·Mitsuo YoshinouchiKenji Yamato
Dec 6, 2003·The Oncologist·Maarten L Janmaat, Giuseppe Giaccone
Feb 12, 2004·Cancer Research·Françoise ThierryChristian Desaintes
Jun 16, 2004·International Journal of Cancer. Journal International Du Cancer·Nubia MuñozChris J L M Meijer
Aug 7, 2004·Human Pathology·Richard B S RodenT-C Wu

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Citations

Apr 4, 2017·Cytokine & Growth Factor Reviews·Fernanda Costa Brandão BertiKaren Brajão de Oliveira
Feb 15, 2020·The Journal of International Medical Research·Xiangfan ChenXiaoyan Li
Mar 28, 2018·BioMed Research International·Renata Prandini Adum de MatosPaula Rahal
Jan 9, 2021·Infectious Agents and Cancer·Lucia Oton-GonzalezFernanda Martini
Jun 14, 2021·Seminars in Cancer Biology·Muhammad Jameel Mughal, Hang Fai Kwok
Aug 1, 2021·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·R Tagne SimoPhélix B Telefo
Oct 8, 2021·International Journal of STD & AIDS·Olivia T Van GerwenChristina A Muzny

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