Overview of linkage analysis in complex traits

Current Protocols in Human Genetics
M A Pericak-Vance

Abstract

The goal of this unit is to instruct the reader on the general approaches now available for mapping complex disease. The term complex genetic disease refers to a trait phenotype with an unknown mode of inheritance. The goal of this unit is to instruct the reader on the general approaches now available for mapping complex disease.

References

Oct 2, 1992·Cell·X JeunemaitreJ M Lalouel
Jan 1, 1985·Genetic Epidemiology·W C Blackwelder, R C Elston
Mar 1, 1972·Behavior Genetics·J K Haseman, R C Elston
Jan 1, 1971·Human Heredity·R C Elston, J Stewart
Jan 1, 1981·Human Heredity·J M Lalouel, N E Morton
Jun 1, 1994·Nature Genetics·G GyapayJ Weissenbach
Aug 1, 1995·Nature Genetics·M S Boguski, G D Schuler
Oct 1, 1994·Nature Genetics·G Thomson
Apr 1, 1995·Nature Genetics·F S Collins
Oct 7, 1994·Science·P A FutrealY Miki
Dec 1, 1995·Trends in Genetics : TIG·M A Pericak-Vance, J L Haines

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