PMID: 16520855Mar 8, 2006Paper

Overview of recent advances in molecular cardiology

The Canadian Journal of Cardiology
Zhongjie Sun

Abstract

Molecular cardiology is a new and fast-growing area of cardiovascular medicine that aims to apply molecular biology techniques for the mechanistic investigation, diagnosis, prevention and treatment of cardiovascular disease. As an emerging discipline, it has changed conceptual thinking of cardiovascular development, disease etiology and pathophysiology. Although molecular cardiology is still at a very early stage, it has opened a promising avenue for understanding and controlling cardiovascular disease. With the rapid development and application of molecular biology techniques, scientists and clinicians are closer to curing heart diseases that were thought to be incurable 20 years ago. There clearly is a need for a more thorough understanding of the molecular mechanisms of cardiovascular diseases to promote the advancement of stem cell therapy and gene therapy for heart diseases. The present paper briefly reviews the state-of-the-art techniques in the following areas of molecular cardiology: gene analysis in the diseased heart; transgenic techniques in cardiac research; gene transfer and gene therapy for cardiovascular disease; and stem cell therapy for cardiovascular disease.

References

Jan 1, 1995·Canadian Journal of Physiology and Pharmacology·Z SunJ R Cade
Jan 1, 1996·Journal of Cardiovascular Pharmacology·B Waeber, H R Brunner
Apr 6, 1999·Trends in Biotechnology·W P Blackstock, M P Weir
May 22, 2003·Cardiovascular Research·Joshua D DowellLoren J Field
Mar 25, 2004·Expert Review of Cardiovascular Therapy·Philippe Menasché
May 17, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Xiuqing WangZhongjie Sun

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

CREs: Gene & Cell Therapy

Gene and cell therapy advances have shown promising outcomes for several diseases. The role of cis-regulatory elements (CREs) is crucial in the design of gene therapy vectors. Here is the latest research on CREs in gene and cell therapy.

Related Papers

Seminars in Thoracic and Cardiovascular Surgery
Lina Nayak, Todd K Rosengart
Current Gene Therapy
Rozenn Quarck, Paul Holvoet
European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V
U LungwitzA Göpferich
© 2021 Meta ULC. All rights reserved