Overview of Skeletal Development.

Methods in Molecular Biology
Tatsuya Kobayashi, Henry M Kronenberg

Abstract

Development of cartilage and bone, the core components of the mouse skeletal system, depends on coordinated proliferation and differentiation of skeletogenic cells, including chondrocytes and osteoblasts. These cells differentiate from common progenitor cells originating in the mesoderm and neural crest. Multiple signaling pathways and transcription factors tightly regulate differentiation and proliferation of skeletal cells. In this chapter, we overview the process of mouse skeletal development and discuss major regulators of skeletal cells at each developmental stage.

Citations

Mar 2, 2021·Curēus·Bruno BordoniLuigi Pianese
May 19, 2021·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·John GarciaAnne M Delany

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